- ￥5800
- Proteintech
- 85905-4-PBS
- 2025年10月09日
- WB, IF/ICC, Indirect ELISA
- Rabbit
- human
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human PTPN1 protein
- 亚型：
IgG
- 保存条件：
Store at -80°C.
- 克隆性：
Recombinant
- 标记物：
Unconjugated
- 适应物种：
human
- 宿主：
Rabbit
- 应用范围：
WB, IF/ICC, Indirect ELISA
- 靶点：
PTPN1/PTP1B
- 抗体英文名：
PTPN1/PTP1B Recombinant monoclonal antibody, PBS Only
- 抗体名：
PTPN1/PTP1B Recombinant monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
85905-4-PBS targets PTPN1/PTP1B in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, IF/ICC, Indirect ELISA |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag1878 Product name: Recombinant human PTPN1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-435 aa of BC015660 Sequence: MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPLNAAPYGIESMSQDTEVRSRVVGGSLRGAQAASPAKGEPSLPEKDEDHALSYWKPFLVNMCVATVLTAGAYLCYRFLFNSNT |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | protein tyrosine phosphatase, non-receptor type 1 |
| 别名 | PTP1B, PTPN1, EC:3.1.3.48, Protein-tyrosine phosphatase 1B, PTP 1B |
| 计算分子量 | 435 aa, 50 kDa |
| 观测分子量 | 50 kDa |
| GenBank蛋白编号 | BC015660 |
| 基因名称 | PTP1B |
| Gene ID (NCBI) | 5770 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P18031 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PTPN1 (protein tyrosine phosphatase, non-receptor type 1) is also named as PTP1B or PTP-1B, and belongs to the protein-tyrosine phosphatase family and non-receptor class 1 subfamily. PTPN1 is involved in the regulation of several important physiological pathways, which regulates both INS and leptin signaling, and interacts with the epidermal-and platelet-derived growth factor receptors (PMID: 20101100). The gene might harbor variants influencing susceptibility to INS resistance and type 2 diabetes (PMID:15919813). The molecular mass of PTPN1 is 50 kDa, but sometimes some truncated forms can be detected as 48, 46, 39, 37 kDa due to non-specific proteolytic cleavage of PTP1B in different cells (PMID: 18253097).
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