- ￥5800
- Proteintech
- 68055-1-PBS
- 2025年10月09日
- IHC, RIP, Dot Blot, ELISA, Indirect ELISA
- Mouse
- chemical compound, m6a
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- 详细信息
- 技术资料
- 亚型：
IgG3
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
chemical compound, m6a
- 宿主：
Mouse
- 应用范围：
IHC, RIP, Dot Blot, ELISA, Indirect ELISA
- 靶点：
m6A
- 抗体英文名：
m6A Monoclonal antibody, PBS Only
- 抗体名：
m6A Monoclonal antibody, PBS Only
- 规格：
100ug
产品信息
68055-1-PBS targets m6A in IHC, RIP, Dot Blot, ELISA, Indirect ELISA applications and shows reactivity with chemical compound, m6a samples.
| 经测试应用 | IHC, RIP, Dot Blot, ELISA, Indirect ELISA |
| 经测试反应性 | chemical compound, m6a |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Mouse / IgG3 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | m6A |
| 别名 | 6-N-Methyladenoside, N6-methyladenosine |
| GenBank蛋白编号 | m6A |
| 基因名称 | |
| Gene ID (NCBI) | |
| RRID | AB_2918796 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
m6A (N6-methyladenosine) is the most abundant internal modification in mammalian mRNA. This modification is installed by the m6A methyltransferases or termed "writers"such as METTL3 and METTL14, and can be reversed by demethylases that serve as "erasers" such as FTO and ALKBH5. The stability of m6A-modified mRNA is regulated by m6A reader protein YTHDFs, which recognizes m6A and reduces the stability of target transcripts. m6A modification and its regulatory proteins play critical roles in cancer pathogenesis and progression. m6A modification is also invovled in viruses life cycles, suggesting that drugs targets to m6A pathway could be used for antiviral thereapy.
Protocol for Dot Blot:
https://www.ptglab.com/protocol/68055-1-IgDotBlot.pdf
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