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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG
- 保存条件:
Store at -80°C.
- 克隆性:
Recombinant
- 标记物:
Unconjugated
- 适应物种:
mouse
- 宿主:
Rabbit
- 应用范围:
FC
- 靶点:
E-selectin/CD62E
- 抗体英文名:
Anti-Mouse E-selectin/CD62E Rabbit Recombinant Antibody, PBS Only
- 抗体名:
Anti-Mouse E-selectin/CD62E Rabbit Recombinant Antibody, PBS Only
- 规格:
500ug/1mg
| 规格: | 500ug | 产品价格: | ¥3600.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥5000.0 |
产品信息
98065-1-PBS targets E-selectin/CD62E in FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC |
| 经测试反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | selectin, endothelial cell |
| 别名 | CD62E, E-selectin, 240700D4, E selectin, Elam |
| 计算分子量 | 67KD |
| GenBank蛋白编号 | NM_011345.2 |
| 基因名称 | Sele |
| Gene ID (NCBI) | 20339 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | Q00690 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
E-selectin, also known as CD62E or ELAM-1, is a member of the selectin family of adhesion molecules that also includes L-selectin and P-selectin. E-selectin is an inducible endothelial cell surface molecule. Its expression on endothelial cells is transcriptionally upregulated by various proinflammatory substances such as IL-1, TNFα and lipopolysaccharide (LPS). Besides, it can be secreted by endothelial cells, and can be detected in a soluble form (sE-selectin) in serum. During inflammation, E-selectin plays an important part in recruiting leukocytes to the site of injury. (PMID: 2827173; 1382417; 8943958)
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文献和实验Immunofluorescence: Rabbit Anti-Murine RELMα
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suspended in PBS. A rabbit polyclonal antisera is also available (101c500; BAbCO) but in our hands this was less reactive. The antibody cleanup protocol is now a seperate document Protocol Cells are grown in 5 mls of YPAD to an O.D. 600
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