- ￥5800
- Proteintech
- 65221-1-PBS
- 2025年10月09日
- FC
- Rat
- mouse
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- 详细信息
- 文献和实验
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- 亚型：
IgG1, kappa
- 保存条件：
Store at -80°C.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
mouse
- 宿主：
Rat
- 应用范围：
FC
- 靶点：
B7-H3/CD276
- 抗体英文名：
Anti-Mouse B7-H3/CD276 (MJ18), PBS Only
- 抗体名：
Anti-Mouse B7-H3/CD276 (MJ18), PBS Only
- 规格：
100ug
产品信息
65221-1-PBS targets B7-H3/CD276 in FC applications and shows reactivity with mouse samples.
| 经测试应用 | FC |
| 经测试反应性 | mouse |
| 免疫原 |
fusion protein |
| 宿主/亚型 | Rat / IgG1, kappa |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | CD276 antigen |
| 别名 | Cd276, CD276 antigen, B7RP 2, B7-H3, B7h3 |
| GenBank蛋白编号 | BC019436 |
| 基因名称 | Cd276 |
| Gene ID (NCBI) | 102657 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein G purification |
| UNIPROT ID | Q8VE98 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD276 (also known as B7-H3) is a type I transmembrane protein expressed on many tissues and cell types. CD276 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, CD276 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063).
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