- ￥2800
- Proteintech
- CL488-84650-4
- 2025年10月09日
- IF/ICC
- Rabbit
- human, rat
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- 详细信息
- 技术资料
- 免疫原：
Recombinant human ARNT,HIF1B protein
- 亚型：
IgG
- 保存条件：
Store at -20°C. Avoid exposure to light. Stable for one year after shipment.
- 克隆性：
Recombinant
- 标记物：
CoraLite® Plus 488 Fluorescent Dye
- 适应物种：
human, rat
- 宿主：
Rabbit
- 应用范围：
IF/ICC
- 靶点：
ARNT/HIF-1 beta
- 抗体英文名：
CoraLite® Plus 488-conjugated ARNT/HIF-1 beta Recombinant monoclonal antibody
- 抗体名：
CoraLite® Plus 488-conjugated ARNT/HIF-1 beta Recombinant monoclonal antibody
- 规格：
100ul
经过测试的应用
| Positive IF/ICC detected in | HepG2 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
CL488-84650-4 targets ARNT/HIF-1 beta in applications and shows reactivity with human, rat samples.
| 经测试应用 | IF/ICC |
| 经测试反应性 | human, rat |
| 免疫原 |
CatNo: Ag5507 Product name: Recombinant human ARNT,HIF1B protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-348 aa of BC060838 Sequence: MAATTANPEMTSDVPSLGPAIASGNSGPGIQGGGAIVQRAIKRRPGLDFDDDGEGNSKFLRCDDDQMSNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQQQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGSSSVDPVSVNRLSFVRNRCRNGLGSVKDGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSS |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | aryl hydrocarbon receptor nuclear translocator |
| 别名 | ARNT, HIF-1 beta, HIF1B, 242111G2, bHLHe2 |
| 计算分子量 | 416 aa, 46 kDa, 87 kDa |
| 观测分子量 | 87 kDa |
| GenBank蛋白编号 | BC060838 |
| 基因名称 | ARNT/HIF-1 beta |
| Gene ID (NCBI) | 405 |
| 偶联类型 | CoraLite® Plus 488 Fluorescent Dye |
| 最大激发/发射波长 | 493 nm / 522 nm |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P27540 |
| 储存缓冲液 | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| 储存条件 | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
HIF1B(HIF-1 beta), also named as ARNT, is a 789 amino acid protein, which forms a heterodimer with AHR, AHRR, HIF1A and EPAS1/HIF2A as well as with other bHLH proteins. HIF1B is Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
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