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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG2a,κ
- 保存条件:
Store at 4℃ in dark.Do not freeze.
- 克隆性:
Monoclonal Antibody
- 标记物:
Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,Solar Fluor 350,Solar Fluor 405,Solar Fluor 488,Solar Fluor 532,Solar Fluor 555,Solar Fluor 568,Solar Fluor 594,Solar Fluor 633,Solar Fluor 640,Solar Fluor 647,Solar Fluor 660,Solar Fluor 680,Solar Fluor 750
- 适应物种:
Human
- 目录编号:
7852
- 级别:
实验级别
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Mouse
- 应用范围:
FCM
- 浓度:
FCM 5uL/Test.
- 靶点:
CD184
- 抗体英文名:
Anti-CD184(PE) Monoclonal Antibody
- 抗体名:
C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Stromal cell-derived factor 1 receptor; SDF-1 receptor; Fusin; Leukocyte-derived seven transmembrane domain receptor; LESTR; CD184 antigen; CXCR4_HUMAN
- 规格:
25T/100T
| 规格: | 25T | 产品价格: | ¥2250.0 |
|---|---|---|---|
| 规格: | 100T | 产品价格: | ¥4550.0 |
| 基本信息 | |
| 英文名称 | Anti-CD184(PE) Monoclonal Antibody |
| 宿主 | Mouse |
| 克隆类型 | Monoclonal Antibody |
| 亚型 | IgG2a,κ |
| 交叉反应 | Human |
| 应用 | FCM |
| 稀释比例 | FCM 5uL/Test. |
| 密度 | |
| 靶标 | CD184 |
| 别名 | C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Stromal cell-derived factor 1 receptor; SDF-1 receptor; Fusin; Leukocyte-derived seven transmembrane domain receptor; LESTR; CD184 antigen; CXCR4_HUMAN |
| 背景说明 | This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts,hypogammaglobulinemia,infections,and myelokathexis) syndrome. Alternate transcriptional splice variants,encoding different isoforms,have been characterized. Monomer. Can form dimers. |
| Swiss Prot | P61073 |
| Gene ID | 7852 |
| 亚细胞定位 | Cell membrane |
| 储存条件 | Store at 4℃ in dark.Do not freeze. |
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文献和实验The Application of Monoclonal Antibodies in the Treatment of Lymphoma
lymphoma treated with a chimeric anti-CD20 mAb, and Maloney and co-workers (2 ) recently reported a 50% response rate in relapsed, low-grade, NHL, with a 10---11 mo duration. Encouragingly, patients in these studies did not raise antibody responses
monoclonal antibodies have improved responses with minimal toxicities. For instance, Rituximab (chimeric anti-CD20 monoclonal antibody) was the first FDA-approved monoclonal antibody for the treatment of patients with non-Hodgkin’s lymphoma (NHL
T-cell dependent antigen specific in situ staining (Pe)
6- Wash twice in TBS-T. 7- counterstain with rabbit anti B-Pe 1:2000 (0.5 µg/ml Cortex Biochem). You may add 1% mouse serum to the anti-Pe antibodies, unless you plan to use mouse monoclonal further (see below). 8- wash twice in TBS-T. 9- block
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