PE anti-human CD184 (CXCR4)

PE anti-human CD184 (CXCR4) Antibody
12G5
Catalog# / Size 306505 / 25 tests
306506 / 100 tests
Clone
Regulatory Status RUO
Workshop VII 70204
Other Names CXCR4, Fusin
Isotype Mouse IgG2a, κ
Description CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked
CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B
and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets,
lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons,
among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood
cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood
vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an
alternative receptor for some isolates of HIV-2.
Product Details
Verified Reactivity Human, Cynomolgus, Rhesus
Reported Reactivity African Green, Baboon, Chimpanzee, Sooty Mangabey
Antibody Type Monoclonal
Host Species Mouse
Immunogen CP-MAC-infected Sup-T1 cells
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation The antibody was purified by affinity chromatography, and conjugated with PE under optimal
conditions.
Concentration Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our
Certificate of Analysis online tool.)
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from
prolonged exposure to light. Do not freeze.