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- 详细信息
- 文献和实验
- 技术资料
- 库存:
150
- 英文名:
pCMV-BRCA1(human)-3×Myc-Neo
- 保质期:
2年
- 供应商:
上海烜雅生物科技有限公司
- 保存条件:
2-8℃
- 规格:
少量干粉质粒/大提液体质粒
| 规格: | 少量干粉质粒 | 产品价格: | ¥780.0 |
|---|---|---|---|
| 规格: | 大提液体质粒 | 产品价格: | ¥980.0 |
别称:NM_001407593.1;BRCAI; BRCC1; BROVCA1; FANCS; IRIS; PNCA4;PPP1R53; PSCP; RNF53
基因长:5589bp
质粒宿主:哺乳细胞
质粒用途:蛋白表达
片段类型:ORF
片段物种:人
原核抗性:Amp
筛选标记:Neo/G418
荧光标记:
启动子:CMV
复制子:pUC
感受态:DH5a
温度:37度
正向引物:CMV-F
反向引物:
注意事项:本产品仅供科研使用,不能用于临床试验,包括人体口服、注射或者体外用药。
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文献和实验Ovarian Cancer Gene Therapy with BRCA1An Overview
The human breast and ovarian cancer susceptibility gene BRCA1 is a tumorsuppressor gene which is mutated and lost in hereditary breast and ovarian cancer, and has both alleles mutated in approximately 10-15% of cases of sporadic ovarian cancer
Development of a Scoring System to Screen for BRCA1/2 Mutations
Selection for genetic testing for pathogenic mutations in BRCA1 and BRCA2 is an important area of healthcare. While testing costs for mutational analysis are falling, costs of tests in North America remain in excess of $3,000. Most countries
Developing Functional Assays for BRCA1 Unclassified Variants
Women with a family history of breast cancer have mutations in one of the breast cancer susceptibility genes, BRCA1 or BRCA2 . Since the discovery of these two genes, around 100,000 women worldwide have undergone genetic testing
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