Anti-FcRγ / FCER1G Recombinant

FcRγ (also known as FCER1G) is a critical signaling adapter protein that associates with various cell surface receptors, particularly those involved in immune responses. It is an essential component of Fc receptors, such as FcεRI and FcγR, which are involved in the binding of immunoglobulin E (IgE) and immunoglobulin G (IgG), respectively. FcRγ plays a crucial role in transmitting intracellular signaling upon ligand binding, leading to the activation of immune cells like mast cells, basophils, dendritic cells, and neutrophils. This signaling is vital for immune responses such as allergic reactions, inflammation, and phagocytosis. The protein is involved in activating downstream signaling pathways, including tyrosine kinase activation, and plays a central role in mediating immune cell activation and degranulation. Due to its involvement in immune cell function, FcRγ is also associated with diseases like allergies, autoimmune disorders, and inflammatory conditions.