- ￥3419.30
- BioLegend
- 163302
- 美国
- 2025年08月12日
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
Purified anti-mouse Siglec-G
- 抗体英文名：
Purified anti-mouse Siglec-G
- 供应商：
上海善然生物科技有限公司
- 保存条件：
2-8℃
- 规格：
100ug
Purified anti-mouse Siglec-G Antibody
SH1
Catalog# / Size 163302 / 100 µg
Clone
Regulatory Status RUO
Other Names Siglec10, Sialic acid-binding Ig-like lectin G
Isotype Mouse IgG1, κ
Description Siglec-G is a member of the CD33-related Siglec (sialic acid–binding, immunoglobulin-like
lectin) family. Siglec-G is the orthologue of human Siglec-10. It is a 110-120 kDa, 688 amino
acid type I transmembrane protein and contains five extracellular immunoglobulin domains
and an intracellular region with three conserved tyrosine-based motifs. It is an inhibitory
receptor that is expressed in a B cell–restricted way, with particularly high expression in Pre-B
and B1a cells. Upon stimulation with an antigen, Siglec-G is recruited to IgM, which is further
phosphorylated inhibiting IgM-induced Ca2+ signaling and NFATc1 expression.
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文献和实验Immunohistochemistry: Mouse Anti-Human MCP-1
. 4. Incubate the tissue section overnight at 4?C with Mouse Anti-Human MCP-1 at 10.0 μg/mL. Wash the slide twice for three minutes each. 5. Incubate the tissue section with the Envision HRP polymer kit (Dako) according to the manufacturer’s
实验步骤 1. Using the AbC™ Anti-Mouse Bead Kit 1) Completely resuspend the AbC™ capture beads (Component A) and negative beads (Component B) by gently vortexing for 30 seconds before use. 2) Label
-purified goat anti-mouse IgG (Jackson Labs; 1 mg/ml stock used at 1:300 dilution) Texas Red-conjugated affinity-purified donkey anti-rabbit (Jackson Labs;1 mg/ml stock used at 1:200 dilution)
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