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Brilliant Violet 785™ anti-hum

an CD274 (B7-H1, PD-L1)
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  • ¥6042
  • BioLegend
  • 329736
  • 美国
  • 2025年07月13日
  • 免疫荧光,流式
  • 小鼠
  • Human Reported Reactivity African Green, Baboon, Cynomolgus, Rhesus
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      Brilliant Violet 785™ anti-human CD274 (B7-H1, PD-L1)

    • 抗体英文名

      Brilliant Violet 785™ anti-human CD274 (B7-H1, PD-L1)

    • 应用范围

      免疫荧光,流式

    • 宿主

      小鼠

    • 供应商

      上海善然生物

    • 库存

      现货

    • 抗原来源

      小鼠

    • 适应物种

      Human Reported Reactivity African Green, Baboon, Cynomolgus, Rhesus

    • 标记物

      Brilliant Violet 785™

    • 克隆性

      单克隆

    • 形态

      液体

    • 规格

      100 tests

    Brilliant Violet 785™ anti-human CD274 (B7-H1, PD-L1) Antibody
    29E.2A3
    Catalog# / Size 329735 / 25 tests
    329736 / 100 tests
    Clone
    Regulatory Status RUO
    Other Names Programmed cell death ligand 1 (PD-L1), B7 homolog 1 (B7-H1)
    Isotype Mouse IgG2b, κ
    Description CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as
    a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the
    stimulatory and inhibitory signals needed for responses to microbes and maintenance of selftolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ
    production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown
    that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance
    T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising
    interesting implications for its expression in a wide variety of cell types, including T and B cells,
    antigen-presenting cells, and nonhematopoietic cells.
    Product Details
    Verified Reactivity Human
    Reported Reactivity African Green, Baboon, Cynomolgus, Rhesus
    Antibody Type Monoclonal
    Host Species Mouse
    Immunogen Full length human PD-L1
    Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
    Preparation The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 785™
    under optimal conditions.
    Concentration Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our
    Certificate of Analysis online tool.)
    Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from
    prolonged exposure to light. Do not freeze.

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    文献支持
    Brilliant Violet 785™ anti-human CD274 (B7-H1, PD-L1)
    ¥6042