- ￥1868
- abinScience
- France
- HB163042
- 2026年03月03日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
- 保质期：
1 year
- 英文名：
Recombinant Human ATF6 Protein, N-GST&C-His
- 库存：
999
- 供应商：
abinScience
- 规格：
100ug
| Product name | Recombinant Human ATF6 Protein, N-GST&C-His |
|---|---|
| Catalog No. | HB163042 |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Purity | >90% as determined by SDS-PAGE. |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Endotoxin level | Please contact with the lab for this information. |
| Expression system | E. coli |
| Accession | P18850 |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Alternative Names | Cyclic AMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 alpha; Activating transcription factor 6 alpha; ATF6-alpha; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; ATF6 |
| Species | Homo sapiens (Human) |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003...
Product categories and application fields.
Main products...
Application field: Infectious disease research, Neuroscience, Immunology, Oncology
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文献和实验• ATF6 aggravates acinar cell apoptosis and injury by regulating p53/AIFM2 transcription in Severe Acute Pancreatitis., PMID:32724472
• ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs., PMID:11163209
• XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor., PMID:11779464
• Proteostasis and Beyond: ATF6 in Ischemic Disease., PMID:31078432
• ATF6 Promotes Colorectal Cancer Growth and Stemness by Regulating the Wnt Pathway., PMID:39324706
• GRINA alleviates hepatic ischemia‒reperfusion injury-induced apoptosis and ER-phagy by enhancing HRD1-mediated ATF6 ubiquitination., PMID:39855351
• Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis., PMID:39905002
• ATF6 is essential for human cone photoreceptor development., PMID:34561305
• ATF6-Mediated Signaling Contributes to PARP Inhibitor Resistance in Ovarian Cancer., PMID:36149636
[资源][原创] 蛋白标签纯化技术——CBP（钙调蛋白结合肽）
缓冲液中能够特异性的被钙调蛋白树脂捕捉吸附，并且在中性环境中能够被2 mM EGTA洗脱，这与6组氨酸亲合标签纯化体系相比反应条件要温和许多。仅有4-kDa 大小的CBP tag 与26-kDa GST 标签相比对蛋白分子的影响非常小。在所表达的蛋白分子上包含一个凝血酶或肠激酶列解位点，依靠它可以非常方便的移除CBP标签。在哺乳动物细胞中表达的标签纯化系统(两步纯化法用于高纯度的要求)Mammalian TAP System本系统同时用到了streptavidin binding peptide
Small Scale GST-Tag Purification Under Nature Conditions
Small Scale GST-Tag Purification Under Nature Conditions According to AMERSHAM-BIOSCIENCES-GST fusion protein Handbook (pdf) Aliquot of Cell Pellet after Induction The idea is to aliquot cells after induction
Preparation of Recombinant Protein Spotted Arrays for Proteome‐Wide Identification of Kinase Targets
, A., Sopko, R., McCartney, R.R., Schmidt, M.C., Rachidi, N., Lee, S.J., Mah, A.S., Meng, L., Stark, M.J., Stern, D.F., De Virgilio, C., Tyers, M., Andrews, B., Gerstein, M., Schweitzer, B., Predki, P.F., and Snyder, M. 2005. Global analysis of protein
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