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- 详细信息
- 技术资料
- 保存条件:
Store at -20℃,2 years.(Avoid freeze/thaw cycles)
- 保质期:
Store at -20℃,2 years.(Avoid freeze/thaw cycles)
- 英文名:
Beta-Amyloid (4-24)
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
10mg/5mg/1mg
| 规格: | 10mg | 产品价格: | ¥4310.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥3080.0 |
| 规格: | 1mg | 产品价格: | ¥1230.0 |
| 基本信息 | |
| 产品类型 | 多肽 |
| CAS | No.103213-49-6 |
| 单字母序列 | EGVNDNEEGFFSAR |
| 三字母序列 | Glu-Gly-Val-Asn-Asp-Asn-Glu-Glu-Gly-Phe-Phe-Ser-Ala-Arg |
| 别名 | 纤维蛋白肽B;[Glu1]Fibrino Peptide B,human;[Glu1]Fibrino Peptide B,human |
| 分子式 | C66H95N19O26 |
| 分子量 | 1570.59 |
| 纯度 | ≥98% |
| 外观(性状) | 冻干粉;Lyophilized powder |
| 盐体系 | TFA盐;Trifluoroacetate salt |
| 来源 | 合成;Synthetic |
| 储存条件 | Store at -20℃,2 years.(Avoid freeze/thaw cycles) |
| 类别/标签 | 心血管研究(Cardiovascular research) |
| 规格 | [Glu1]-Fibrinopeptide B 衍生自纤维蛋白肽B氨基酸残基1-14。人纤维蛋白肽B(hFpB)是来自纤维蛋白原B β链的凝血酶衍生的蛋白水解裂解产物,可用于刺激中性粒细胞 (PMN),单核细胞和成纤维细胞。[Glu1]-Fibrinopeptide B is derived from fibrinopeptide B amino acid residues 1-14. Human fibrinopeptide B (hFpB), a thrombin-derived proteolytic cleavage product of the fibrinogen B beta-chain, to stimulate neutrophils (PMN), monocytes, and fibroblasts. |
| In Vitro | hFpB causes directed cell migration of PMN and fibroblasts that is optimal at approximately 10 nM. hFpB causes a rapid, dose-dependent increase in PMN cytoskeletal associated actin, but unlike fMLP, hFpB does not cause PMN aggregation, release of lysosomal enzymes (lysozyme and beta-glucuronidase), or the production of superoxide anion. These results suggest that hFpB may have a role in recruiting PMN and fibroblasts at sites of fibrin deposition and turnover. The capacity of hFpB to cause PMN chemotaxis without causing concurrent release of lysosomal enzymes or the production of superoxide anion is further evidence for the complexity of PMN responses to chemotactic agents. |
| 单位 | 瓶 |
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CLP0214 Beta-Amyloid (4-24) 淀粉样肽
¥1230 - 4310






