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P01027 Recombinant Mouse TRAIL

R2/TNFRSF10B/CD262/DR5/KILLER/Fas-like protein 细胞因子/蛋白
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  • ¥988 - 21120
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  • P01027
  • 北京
  • 2025年07月25日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现询

    • 供应商

      北京索莱宝科技有限公司

    • 规格

      1mg/500ug/50ug/10ug

    规格:1mg产品价格:¥21120.0
    规格:500ug产品价格:¥14784.0
    规格:50ug产品价格:¥2600.0
    规格:10ug产品价格:¥988.0
    基本信息
    基因名
    别名Tumor necrosis factor receptor superfamily member 10B/Death receptor 5/MK/CD262/Tnfrsf10b/Dr5/Killer
    外观(性状)Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
    纯度≥90% as determined by reducing SDS-PAGE.
    储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
    运输条件The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below.
    背景说明Mouse tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats.TNFRSF10B exhibits high structural and functional homology to TRAIL-R1 (DR-4).TNFRSF10B is highly expressed in heart,lung,lymphocytes,spleen and kidney.In addition,it is regulated by the tumor suppressor p53.TNFRSF10B is the receptor for the cytotoxic ligand TNFSF10/TRAIL.It promotes the activation of NF-kappa-B and is essential for ER stress-induced apoptosis.The adapter molecule FADD recruits caspase-8 to the activated receptor.The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis.
    来源Human Cells
    溶剂Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    内毒素Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
    单位

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    • Mouse Strains and Genetic Nomenclature

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