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- 详细信息
- 文献和实验
- 技术资料
- 库存:
现询
- 供应商:
北京索莱宝科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥8160.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥6240.0 |
| 规格: | 50ug | 产品价格: | ¥1560.0 |
| 规格: | 10ug | 产品价格: | ¥520.0 |
| 基本信息 | |
| 基因名 | |
| 别名 | Tumor Necrosis Factor Receptor Superfamily Member 10B;Death Receptor 5;TNF-Related Apoptosis-Inducing Ligand Receptor 2;TRAIL Receptor 2;TRAIL-R2;CD262;TNFRSF10B;DR5;KILLER;TRAILR2;TRICK2;ZTNFR9 |
| 中文名称 | Recombinant Human TRAIL R2/TNFRSF10B/CD262/DR5/KILLER/Fas-like protein |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | TNFRSF10B is a member of the TNF-receptor superfamily,and contains an intracellular death domain.This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L),and transduces apoptosis signal.The adapter molecule FADD recruits caspase-8 to the activated receptor and is required for the apoptosis mediated by TNFRSF10B.TNFRSF10B is expressed in a number of cell types,and to particularly high levels in lymphocytes and spleen.This single-pass transmembrane protein contains two cysteine-rich repeat units in its extracellular region,followed by a transmembrane segment and a cytoplasmic tail containing a typical “death domain”.TNFRSF10B expression is regulated by the tumor suppressor p53.It is also indicated that the activation of NF-kappa-B can be promoted by TNFRSF10B. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
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