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- 详细信息
- 文献和实验
- 技术资料
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 规格：
1mg/500ug/50ug/10ug
| 规格： | 1mg | 产品价格： | ￥16896.0 |
|---|---|---|---|
| 规格： | 500ug | 产品价格： | ￥11808.0 |
| 规格： | 50ug | 产品价格： | ￥3276.0 |
| 规格： | 10ug | 产品价格： | ￥1092.0 |
Recombinant Human Sonic Hedgehog is produced by our E.coli expression system and the target gene encoding Cys24-Gly197 is expressed.
【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:The enhanced generation of motor neurons from mESCs by MgAl layered double hydroxide nanoparticles
成员:Yuxin Bai, Zhaojie Wang, Liqun Yu, Kun Dong, Liming Cheng, Rongrong Zhu
论文因子:4 发表期刊:Biomedical Materials pmid:36898160
| 基本信息 | |
| 基因名 | |
| 别名 | Sonic Hedgehog Protein;SHH;HHG-1 |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 100mM NaCl, 1mM DTT, pH 7.5. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | The product is shipped at 2-8°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| 背景说明 | Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called hedgehog.The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH).Hedgehog proteins are key signaling molecules in embryonic development.SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems，such as limbs and brain.SHH also plays an important role in adult，including the division of adult stem cells and the development of certain cancers and other diseases.Human SHH is expressed as a 45kDa precursor，and undergoes a series of processing during secretion.After the removal of the signal peptide，a protease within the C-terminal domain catalyzes the cleavage of SHH into a 20 kDa N-terminal signaling domain (SHH-N) and a 25 kDa C-terminal domain (SHH-C).SHH-N has the “all signaling” capability.SHH-N binds to the 12 pass transmembrane protein Patched (Ptc) on cell surface，which releases the repression of the activity of Smoothened (Smo)，a G-protein coupled receptor，by Ptc. |
| 来源 | E.coli |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 IEU/ug)as determined by LAL test. |
| 单位 | 支 |
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文献和实验【本资料源自公开渠道，如需（此处）屏蔽，请联系删除】
标题:The enhanced generation of motor neurons from mESCs by MgAl layered double hydroxide nanoparticles
成员:Yuxin Bai, Zhaojie Wang, Liqun Yu, Kun Dong, Liming Cheng, Rongrong Zhu
论文因子:4 发表期刊:Biomedical Materials pmid:36898160
Abstract: Sonic Hedgehog is an essential glycoprotein integral for the proper craniofacial and tail bud development, in addition to the development of many other structures. Cyclopamine has been shown to block Shh, and cause
Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
Dopaminergic Neuronal Differentiation Protocol for Human Mesenchymal Stem Cells
from the adult human bone marrow (BM) can be easily isolated and expanded in culture while maintaining their immense plasticity. Here, we describe a protocol to generate DA-producing cells from adult human MSCs using a cocktail that includes sonic hedgehog (SHH
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