SDA 炔烃

SDA 炔烃

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  • ¥986
  • AAT Bioquest
  • 进口
  • 39005
  • 2025年07月15日
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    • 详细信息
    • 技术资料
    • 英文名

      SDA alkyne

    • 库存

      50

    • 供应商

      广州市左克生物科技发展有限公司

    • 规格

      1mg

    产品参数
    Ex (nm)-Em (nm)-
    分子量N/A溶剂DMSO
    存储条件在零下15度以下保存, 避免光照
    产品概述

    产品基本信息

    产品名称:SDA 炔烃

    储存条件:-15℃避光防潮

    保质期:24个月

     

    产品物理化学光谱特性

    分子量:195.20

    外观:橙色粉末

    溶剂:DMSO

    激发波长(nm):N/A

    发射波长(nm):N/A

     

    产品介绍

    SDA 炔包含二氮丙啶光亲和部分和炔官能团。它是通过众所周知的点击化学将光亲和功能引入叠氮化物修饰的生物分子的出色构建模块。二氮丙啶以其在暴露于紫外线 (UV) 时发生光化学反应的能力而闻名,特别是通过形成高反应性卡宾中间体,与附近的分子发生反应,形成共价键。这一特性使得二氮丙啶可用于研究蛋白质-蛋白质、蛋白质-核酸相互作用、配体-受体结合和其他生物分子相互作用。值得注意的是,二氮丙啶具有高度反应性,并且由于其不稳定性而难以处理。它们需要小心储存和处理,通常是在受控环境中。此外,必须仔细优化含二氮丙啶化合物的选择和光标记实验条件,以实现所需结果,同时最大限度地减少非特异性反应。

     

    溶解方案(溶剂以说明书为准)

      0.1 mg 0.5 mg 1 mg 5 mg 10 mg
    1 mM 605.327 µL 3.027 mL 6.053 mL 30.266 mL 60.533 mL
    5 mM 121.065 µL 605.327 µL 1.211 mL 6.053 mL 12.107 mL
    10 mM 60.533 µL 302.663 µL 605.327 µL 3.027 mL 6.053 mL

     

    参考文献

    A tumor-targetable NIR probe with photoaffinity crosslinking characteristics for enhanced imaging-guided cancer phototherapy.
    Authors: Sun, Rui and Zhang, Yuqi and Gao, Yinjia and Zhao, Meng and Wang, Anna and Zhu, Jinfeng and Cheng, Xiaju and Shi, Haibin
    Journal: Chemical science (2023): 2369-2378
     
    Photoaffinity labelling-based chemoproteomic strategy identifies PEBP1 as the target of ethyl gallate against macrophage activation.
    Authors: Yu, Wei and Liao, Min and Chen, Yang and Xue, Rui and Shi, Xiao-Meng and Liu, Dan and Zhuo, Fang-Fang and Tang, Hui and Lu, Zhi-Yuan and Tu, Peng-Fei and Han, Bo and Jia, Xin and Zeng, Ke-Wu
    Journal: Chemical communications (Cambridge, England) (2023): 1022-1025
     
    Pepstatin-Based Probes for Photoaffinity Labeling of Aspartic Proteases and Application to Target Identification.
    Authors: Chen, Suyuan and Liang, Chunguang and Li, Hongli and Yu, Weimeng and Prothiwa, Michaela and Kopczynski, Dominik and Loroch, Stefan and Fransen, Marc and Verhelst, Steven H L
    Journal: ACS chemical biology (2023): 686-692
     
    Exploring a chemical scaffold for rapid and selective photoaffinity labelling of non-ribosomal peptide synthetases in living bacterial cells.
    Authors: Ishikawa, Fumihiro and Konno, Sho and Uchiyama, Yuko and Kakeya, Hideaki and Tanabe, Genzoh
    Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences (2023): 20220026
     
    A photoaffinity glycan-labeling approach to investigate immunoglobulin glycan-binding partners.
    Authors: Holborough-Kerkvliet, Miles D and Mucignato, Greta and Moons, Sam J and Psomiadou, Venetia and Konada, Rohit S R and Pedowitz, Nichole J and Pratt, Matthew R and Kissel, Theresa and Koeleman, Carolien A M and Tjokrodirijo, Rayman T N and van Veelen, Petrus A and Huizinga, Thomas and van Schie, Karin A J and Wuhrer, Manfred and Kohler, Jennifer J and Bonger, Kimberly M and Boltje, Thomas J and Toes, Reinaldus E M
    Journal: Glycobiology (2023): 732-744
     
    Design and Evaluation of a Cyclobutane Diazirine Alkyne Tag for Photoaffinity Labeling in Cells.
    Authors: West, Alexander V and Amako, Yuka and Woo, Christina M
    Journal: Journal of the American Chemical Society (2022): 21174-21183
     
    Expanded Application of a Photoaffinity Probe to Study Epidermal Growth Factor Receptor Tyrosine Kinase with Functional Activity.
    Authors: Deng, Hui and Lei, Qian and Yang, Na and Dai, Shengkun and Peng, Huipai and Yang, Kai and Xiao, Zhaolin and Wang, Dongpeng and Yu, Zhiyi and Li, Nan and Li, Weimin
    Journal: Analytical chemistry (2022): 10118-10126
     
    Photoaffinity labeling approaches to elucidate lipid-protein interactions.
    Authors: Yu, Weizhi and Baskin, Jeremy M
    Journal: Current opinion in chemical biology (2022): 102173
     
    Photoaffinity labeling and bioorthogonal ligation: Two critical tools for designing "Fish Hooks" to scout for target proteins.
    Authors: Karaj, Endri and Sindi, Shaimaa H and Viranga Tillekeratne, L M
    Journal: Bioorganic & medicinal chemistry (2022): 116721
     
    Selective Photoaffinity Probe for Monitoring Farnesoid X Receptor Expression in Cultured Cells.
    Authors: Xu, Xiao-Wei and Zhu, Ya and Song, Jiang-Zhou and Zou, Gui-Qing and Zhao, Zhou and Zheng, Qiu-Ling and Cao, Li-Juan and Wang, Guang-Ji and Wang, Hong and Hao, Hai-Ping
    Journal: Analytical chemistry (2022): 10722-10729

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