- ￥2260
- LSM Bio
- 进口
- PAab09426
- 2025年07月16日
- ELISA,WB,IF,FC,IP
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
vacuolar protein sorting 11 homolog (S. cerevisiae)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
O95498
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IF,FC,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
vacuolar protein sorting 11 homolog (S. cerevisiae)
- 抗体英文名：
anti-VPS11 antibody,VPS11 antibody
- 抗体名：
anti-VPS11 抗体,VPS11 抗体
- 规格：
100μl
VPS11抗体| VPS11 antibody
货号 PAab09426
蛋白别名 END1 antibody, hVPS11 antibody, PEP5 antibody, RING finger protein 108 antibody, RNF108 antibody, VPS11
蛋白介绍
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for fusion of endosomes and autophagosomes with lysosomes (PubMed:25783203). Involved in cargo transport from early to late endosomes and required for the transition from early to late endosomes (PubMed:21148287). Involved in the retrograde Shiga toxin transport (PubMed:23593995).
产品描述
anti-VPS11 antibody is a Rabbit Polyclonal antibody againstVPS11..
建议稀释比例
WB :1:500-1:5000;IF:1:10-1:100;IP:1:200-1:2000;FC:N/A
IHC
Western blot
human brain tissue were subjected to SDS PAGE followed by western blot with PAab09426(VPS11 antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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