InvivoCrown In vivo NK cell de

InVivoPro Anti-Mouse NK1.1(CD161) Antibody in vivo antibody, Clone PK136InVivoPro Anti-Mouse NK1.1(CD161) Antibody in vivo antibody, Clone PK136Mouse IgG2a κMouse IgG2a κPK136PK136NK1.1NK1.1CD161 antigen, CD161, CD161/NK1.1CD161 antigen, CD161, CD161/NK1.1Mouse IgG2a Isotype ControlMouse IgG2a Isotype ControlPBS, pH 7.2, contains no stabilizers or preservativesPBS, pH 7.2, contains no stabilizers or preservativesMouseMouseMouseMouse200-500 μg per mouse; or 10-20 mg/kg. This range is based off the most recent publication data using the PK136 clone in vivo. Each investigator should determine their own optimal working dilution for specific applications.200-500 μg per mouse; or 10-20 mg/kg. This range is based off the most recent publication data using the PK136 clone in vivo. Each investigator should determine their own optimal working dilution for specific applications.267267Andre, Pascale et al. "Anti-NKG2A Mab is a Checkpoint Inhibitor That Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells",Cell 175.7 (2018): 1731-+. Biswas, Subir et al. "IgA Transcytosis and Antigen Recognition Govern Ovarian Cancer Immunity.",Nature 591.7850 (2021): 464-470. Deng, Zihou et al. "The Nuclear Factor ID3 Endows Macrophages with a Potent Anti-Tumour Activity",NATURE 626.8000 (2024)Andre, Pascale et al. "Anti-NKG2A Mab is a Checkpoint Inhibitor That Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells",Cell 175.7 (2018): 1731-+. Biswas, Subir et al. "IgA Transcytosis and Antigen Recognition Govern Ovarian Cancer Immunity.",Nature 591.7850 (2021): 464-470. Deng, Zihou et al. "The Nuclear Factor ID3 Endows Macrophages with a Potent Anti-Tumour Activity",NATURE 626.8000 (2024)NK-1.1 surface antigen, also known as CD161b/CD161c, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.NK-1.1 surface antigen, also known as CD161b/CD161c, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.In vivo NK cell depletion, Flow cytometryIn vivo NK cell depletion, Flow cytometryprotein A or Gprotein A or GThis antibody is stable for at least 2 months when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C or -80°C. Avoid repeated freeze thaw cycles.This antibody is stable for at least 2 months when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C or -80°C. Avoid repeated freeze thaw cycles.2-8°C with blue ice2-8°C with blue iceLot specific, generally ≥ 5.0 mg/mlLot specific, generally ≥ 5.0 mg/ml12 months from the date of receipt if stored as recommended12 months from the date of receipt if stored as recommendedPBS Buffer, PH 7.2, with no carrier protein, or preservatives.PBS Buffer, PH 7.2, with no carrier protein, or preservatives.0.2 μM filtered0.2 μM filtered≤ 1.0 EU/mg, by the LAL method≤ 1.0 EU/mg, by the LAL method0.990.99可替换BioXCell产品货号为BE0036