- ￥5444
- BioLegend
- 128814
- 美国
- 2026年05月28日
- 免疫荧光，流式
- 大鼠
- 小鼠
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- 文献和实验
- 技术资料
- 抗体名：
PerCP/Cyanine5.5 anti-mouse CD226 (DNAM-1)
- 抗体英文名：
PerCP/Cyanine5.5 anti-mouse CD226 (DNAM-1)
- 浓度：
0.2 mg/ml
- 应用范围：
免疫荧光，流式
- 宿主：
大鼠
- 供应商：
上海善然生物
- 库存：
现货
- 抗原来源：
大鼠
- 适应物种：
小鼠
- 标记物：
PerCP/Cyanine5.5
- 克隆性：
单克隆
- 保存条件：
2-8度
- 形态：
液体
- 规格：
100 μg
PerCP/Cyanine5.5 anti-mouse CD226 (DNAM-1) Antibody
10E5
Catalog# / Size 128813 / 25 µg
128814 / 100 µg
Clone
Regulatory Status RUO
Other Names DNAM-1, PTA1 (platelet and T cell activation antigen 1), TLISA1, LFA-1 associated Molecule
PTA-1
Isotype Rat IgG2b, κ
Description CD226 (DNAM-1) is constitutively expressed on native CD8 cells and on CD4 T cells,
macrophages and NK cells.This antibody (10E5) was reported to bind about 40% of
inactivated CD4 cells and binds only to differentiated Th1 cells, but not to Th2 or Th0 cells.It
is also reported to suppress antigen-specific T cell expansion and EAE (experimental allergic
encephalitis) mediated by Th1 cells.
+ +
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Product Details
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Immunogen Th1 polarized T cell clones
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5
under optimal conditions.
Concentration 0.2 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from
prolonged exposure to light. Do not fr
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不只是 PD-1：CD96 正成为免疫治疗的下一个“必争之地”
结合的关键区域 [8]。CD155 同样属于 Ig 超家族，其胞外区由三个 Ig 样结构域组成，CD96 主要通过自身 IgV 结构域与 CD155 的 N 端 IgV 结构域相互识别 [8]。 3.2 CD96、TIGIT、CD226 免疫调控网络 CD96、TIGIT 和共刺激受体 CD226（DNAM-1）共同构成一个复杂的免疫调控网络，它们共享 CD155 和 CD112 等配体，在免疫激活与抑制之间形成动态平衡 [1],[9]。其中，TIGIT 可与 CD155 和 CD112 结合
Fluorochrome Absorption and Emission Spectra
. Due to its photobleaching characteristics, PerCP conjugates are not recommended for use on stream-in-air flow cytometers. PerCP-Cy5.5 is a tandem conjugate system than combines PerCP with a cyanine dye (Cy5.5™) and has an absorption maximum
Fluorochrome Absorption and Emission
. Due to its photobleaching characteristics, PerCP conjugates are not recommended for use on stream-in-air flow cytometers. PerCP-Cy5.5 is a tandem conjugate system than combines PerCP with a cyanine dye (Cy5.5™) and has an absorption maximum
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