- ￥1620
- BHcell（博辉生物）
- H-C717
- 2025年12月25日
企业认证
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 规格：
T25
UMNSAH/DF-1细胞系、UMNSAH/DF-1细胞株、UMNSAH/DF-1细胞、UMNSAH/DF-1鸡胚胎成纤维细胞
Cell line name UMNSAH/DF-1
Synonyms UMNSAH-DF-1; UMNSAH-DF 1; UMNSAH-DF1; UMNSAH/DF1; UMNSAH/DF#1; DF-1; DF1; Douglas Foster-1
Accession CVCL_0570
Resource Identification Initiative To cite this cell line use: UMNSAH/DF-1 (RRID:CVCL_0570)
Comments Group: Bird cell line.
Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12203.
Virology: Low susceptibility to infection by aquatic bird bornavirus 1 (ABBV-1) strain UoG-CG (PubMed=32005267).
Doubling time: 13.22 hours (Note=In DMEM/F-12 medium), 33.64 hours (Note=In MEM medium), 15.30 hours (Note=In RPMI 1640 medium), 21.39 hours (Note=In DMEM medium) (CelloPub=CLPUB00401).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: East Lansing Line 0 (ELL-0).
Hierarchy Children:
CVCL_A4AG (DF-1 O/E-ST3) CVCL_A4AH (DF-1 O/E-ST3T2) CVCL_A4AI (DF-1 O/E-T2)
CVCL_A4AJ (DF-1 O/E-T4) CVCL_A9LC (DF-1-AvBD2) CVCL_B7JM (DF-1-AvBD9)
CVCL_XF08 (DF-1/A) CVCL_XF09 (DF-1/B) CVCL_XF10 (DF-1/K)
CVCL_XF11 (DF-1\J) CVCL_D6B3 (HyCyte DF1 KO-ggaSERBP1) CVCL_B6MR (LF-1)
Sex of cell Sex unspecified
Age at sampling 10FD
Category Spontaneously immortalized cell line
PubMed=9721238; DOI=10.1006/viro.1998.9290
Himly M., Foster D.N., Bottoli I., Iacovoni J.S., Vogt P.K.
The DF-1 chicken fibroblast cell line: transformation induced by diverse oncogenes and cell death resulting from infection by avian leukosis viruses.
Virology 248:295-304(1998)
PubMed=9721239; DOI=10.1006/viro.1998.9291
Schaefer-Klein J., Givol I., Barsov E.V., Whitcomb J.M., VanBrocklin M., Foster D.N., Federspiel M.J., Hughes S.H.
The EV-O-derived cell line DF-1 supports the efficient replication of avian leukosis-sarcoma viruses and vectors.
Virology 248:305-311(1998)
Patent=US6207415
Foster D.N., Foster L.K.
Immortalized cell lines protein production.
Patent number US6207415, 27-Mar-2001
PubMed=11420679; DOI=10.1038/sj.onc.1204378
Kim H., You S., Kim I.-J., Foster L.K., Farris J., Ambady S., Ponce de Leon F.A., Foster D.N.
Alterations in p53 and E2F-1 function common to immortalized chicken embryo fibroblasts.
Oncogene 20:2671-2682(2001)
PubMed=11513975; DOI=10.1016/S0167-4889(01)00131-8
Kim H., You S., Kong B.-W., Foster L.K., Farris J., Foster D.N.
Necrotic cell death by hydrogen peroxide in immortal DF-1 chicken embryo fibroblast cells expressing deregulated MnSOD and catalase.
Biochim. Biophys. Acta 1540:137-146(2001)
PubMed=16313905; DOI=10.1016/j.febslet.2005.10.066
Christman S.A., Kong B.-W., Landry M.M., Kim H., Foster D.N.
Modulation of p53 expression and its role in the conversion to a fully immortalized chicken embryo fibroblast line.
FEBS Lett. 579:6705-6715(2005)
CLPUB00401
Arifin M.A., Mel M., Raus R.A., Sharifah S.H., Ideris A.
Comparison of growth rate and viability of DF-1 cell line in different culture media.
(In conference) Abstracts of the 2nd international conference on science and technology (ICSTIE 2008); pp.1-5; Universiti Teknologi MARA; Pulau Pinang; Malaysia (2008)
PubMed=18638503; DOI=10.1016/j.jviromet.2008.06.019
Lee C.-W., Jung K., Jadhao S.J., Suarez D.L.
Evaluation of chicken-origin (DF-1) and quail-origin (QT-6) fibroblast cell lines for replication of avian influenza viruses.
J. Virol. Methods 153:22-28(2008)
PubMed=19941903; DOI=10.1016/j.jviromet.2009.11.022
Karger A., Bettin B., Lenk M., Mettenleiter T.C.
Rapid characterisation of cell cultures by matrix-assisted laser desorption/ionisation mass spectrometric typing.
J. Virol. Methods 164:116-121(2010)
PubMed=22111699; DOI=10.1186/1471-2164-12-571; PMCID=PMC3258366
Kong B.-W., Lee J.Y., Bottje W.G., Lassiter K., Lee J., Foster D.N.
Genome-wide differential gene expression in immortalized DF-1 chicken embryo fibroblast cell line.
BMC Genomics 12:571.1-571.19(2011)
Patent=US20200179507
Foster D.N., Foster L.K.
Immortalized cell lines and methods of use.
Patent number US20200179507, 11-Jun-2020
PubMed=32005267; DOI=10.1186/s12985-020-1286-6; PMCID=PMC6995091
Pham P.H., Leacy A., Deng L., Nagy E., Susta L.
Isolation of Ontario aquatic bird bornavirus 1 and characterization of its replication in immortalized avian cell lines.
Virol. J. 17:16.1-16.12(2020)
PubMed=33743496; DOI=10.1016/j.psj.2021.101057; PMCID=PMC8010516
Lee J., Kim D.-H., Suh Y., Lee K.
Research note: potential usage of DF-1 cell line as a new cell model for avian adipogenesis.
Poult. Sci. 100:101057.1-101057.4(2021)
PubMed=34737324; DOI=10.1038/s41598-021-00779-5; PMCID=PMC8569163
Lung O., Candlish R.C., Nebroski M., Kruckiewicz P., Buchanan C., Moniwa M.
High-throughput sequencing for species authentication and contamination detection of 63 cell lines.
Sci. Rep. 11:21657-21657(2021)
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验*发表【中文论文】请标注：由博辉生物科技（广州）有限公司提供； *发表【英文论文】请标注：From Bohui Biological Technology (Guangzhou) Co., Ltd.
样本，寻找ING4基因表达的证据。他们发现低等级肿瘤中的ING4基因表达水平比正常细胞低2到3倍，高等级神经胶质瘤中的ING4表达水平甚至比正常细胞低6倍。另外一次比较脑瘤组织样本与附近正常组织样本的类似检查还发现正常组织内ING4含量丰富，而肿瘤组织内的ING4 水平显著减少。 为研究该蛋白对血管发生的影响，研究人员创造出ING4表达水平比对照肿瘤或高或低的肿瘤细胞系。这些细胞系中的细胞以及正常肿瘤都被植入脑窗（Cranial Window）中，脑窗是老鼠头盖部分嵌入的透明窗，可以观察头部的血管
,2F12;CRIS-3 Leu LFA-1(gp180/95)的α链 与ICAM-1（CD54）和ICAM-2（CD102）结合 CD11b Mol,OKM1; (Mac-1,CR3,integrin αm G,M,NK gp165/95的α链 C3bi和FB受体，与ICAM-1结合，粘附，调理吞噬 CD11c LeuM5;(CR4,integrin αx) M,G,NK,Tsub gp150/95的α链 C3bi受体，调理吞噬
-sylphosphatidylinositol,GPI）连接方式“锚”在细胞膜上。少数白细胞分化抗原是碳水化合物半抗原。白细胞分化抗原参与机体重要的生理和病理过程。假如：（1）免疫应答过程中免疫细胞的相互识别，免疫细胞抗原识别、活化、增殖和分化，免疫效应功能的发挥；（2）造血细胞的分化和造血过程的调控；（3）炎症发生；（4）细胞的迁移如肿瘤细胞的转移等。 第一节 白细胞分化抗原的分类 80年代初以来，由于单克隆抗体，分子克隆、基因转染细胞系等技术在白细胞分化抗原研究中得到广泛深入的应用，有关白细胞分化抗原的研究
技术资料
