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In Vivo Grade Recombinant Anti

-mouse PD-1 Mouse IgG2a Kappa Monoclonal Antibody (Clone 29F.1A12.1)
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  • ¥4000
  • Syd Labs已认证
  • 美国
  • PA007163.m2a
  • 2026年01月09日
  • ELISA, WB, Flow cytometry, IHC, ICC, animal model study
  • Mouse
  • Mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      The original rat hybridoma (clone name: 29F.1A12) was generated by immunizing rats with the mouse PD-1 cDNA followed by the mouse PD-1-Ig fusion protein.

    • 亚型

      Mouse IgG2a Kappa

    • 形态

      Liquid

    • 保存条件

      Store at 2-8℃ and protected from prolonged exposure to light. Avoid freeze/thaw cycles.

    • 克隆性

      Monoclonal Antibody

    • 适应物种

      Mouse

    • 保质期

      如果保存在2 至 8°C,自收到之日起可保存1个月。如果保存在-20 至 -70°C,自收到之日起可保存 12个月。

    • 抗原来源

      The original rat hybridoma (clone name: 29F.1A12) was generated by immunizing rats with the mouse PD-1 cDNA followed by the mouse PD-1-Ig fusion protein.

    • 库存

      3 weeks

    • 供应商

      青木生物技术(武汉)有限公司

    • 宿主

      Mouse

    • 应用范围

      ELISA, WB, Flow cytometry, IHC, ICC, animal model study

    • 浓度

      以实际发货为准

    • 靶点

      PD-1

    • 抗体英文名

      In Vivo Grade Recombinant Anti-mouse PD-1 Mouse IgG2a Kappa Monoclonal Antibody (Clone 29F.1A12.1)

    • 抗体名

      In Vivo Grade Recombinant Anti-mouse PD-1 Mouse IgG2a Kappa Monoclonal Antibody (Clone 29F.1A12.1)

    • 规格

      5mg

    The rat anti-mouse PD-1 monoclonal antibody 29F.1A12 (rat IgG2a kappa) reacts with the mouse PD-1 protein (programmed death-1 or CD279) encoded by the mouse Pdcd1 gene, a member of the CD28 family of the Ig superfamily. PD-1 has two ligands, PD-L1 and PD-L2, both of which belong to the B7 family. It has been shown that in mouse models of melanoma, tumor growth can be transiently arrested via treatment with the anti-mouse PD-1 and anti-mouse PD-L1 antibodies which block the interaction between the PD-L1 protein and its receptor PD-1 protein. The 29F.1A12 monoclonal antibody blocks the binding of both the mouse PD-L1 protein and the mouse PD-L2 protein to the mouse PD-1 protein. Our recombinant 29F.1A12 antibodies have a part (variable regions) or complete amino acid sequences of the rat anti-mouse PD-1 monoclonal antibody (hybridoma clone name or number: 29F.1A12).

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    图标文献和实验
    相关实验
    • Rapid Isotyping of Mouse Monoclonal Antibodies

      from serum, valence, and avidity, all depend on isotype. Isotyping is a basis for the selection of antibody purification, conjugation, fragmentation, and storage procedures, and predicts cytotoxic properties and half-life in vivo (see Note 1 ). In addition

    • Production of Monoclonal Antibody by DNA Immunization with Electroporation

      construct was injected intramuscularly with in vivo electroporation into mice, and the specific antibody production in mice was analyzed by enzyme-linked immunosorbent assay (ELISA). Hybridomas were generated by fusing mouse splenocytes with myeloma cells

    • 【翻译】Development trends for monoclonal antibody cancer therapeutics

      ). However, since 2000, humanized and human mAbs have been entering clinical study at approximately the same rate (4.3 versus 4.5 mAbs per year, respectively). Figure 1 | Categories of monoclonal antibody cancer therapeutics entering clinical study during 1980–1989

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