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- 详细信息
- 文献和实验
- 技术资料
- 库存:
100
- 供应商:
艾美捷科技
- 英文名:
CRE/CREB Luciferase Reporter CHO Cell Line (cAMP/PKA Signaling Pathway)
- 规格:
2 vials
CRE/CREB 荧光素酶报告基因 CHO 细胞系(cAMP/PKA 信号通路),CRE/CREB Luciferase Reporter CHO Cell Line (cAMP/PKA Signaling Pathway),CRE/CREB 荧光素酶报告基因 CHO 细胞系(cAMP/PKA 信号通路),CRE/CREB Luciferase Reporter CHO Cell Line (cAMP/PKA Signaling Pathway)
CRE/CREB 荧光素酶报告基因 CHO 细胞系(cAMP/PKA 信号通路)-CRE/CREB Luciferase Reporter CHO Cell Line (cAMP/PKA Signaling Pathway)
产品货号:BPS-78568
产品规格:2 vials

环腺苷酸(cAMP)是参与调节各种生理和病理过程的细胞信号传导的第二信使。cAMP通过激活蛋白激酶a(PKA)和下游效应子转录因子cAMP反应元件结合蛋白(CREB)来调节靶基因的转录。CRE是许多细胞外和细胞内信号传导途径的靶标,包括cAMP,钙,GPCR(g蛋白偶联受体)和神经营养因子。在cAMP/PKA信号通路中,CREB通过PKA介导的磷酸化被激活,并与CRE结合,一般基序为5’-TGACGTCA-3’。cAMP/PKA/CREB信号通路在肿瘤细胞中具有抑制肿瘤和促进肿瘤的作用,可用于研究肿瘤信号通路。

•监测cAMP/PKA信号通路活动。•筛选cAMP/PKA信号通路的激活剂或抑制剂。

CRE/CREB 荧光素酶报告基因 CHO 细胞系(cAMP/PKA 信号通路)-CRE/CREB Luciferase Reporter CHO Cell Line (cAMP/PKA Signaling Pathway)细胞用干冰运输,收到后应立即解冻或储存在液氮中。不要使用-80摄氏度的冷冻机进行长期储存。
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