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- 详细信息
- 文献和实验
- 技术资料
- 库存:
100
- 供应商:
艾美捷科技
- 英文名:
GITR / NF-κB Luciferase Reporter - Jurkat Cell Line
- 规格:
2 vials
GITR / NF-κB 荧光素酶报告基因 - Jurkat 细胞系,GITR / NF-κB Luciferase Reporter - Jurkat Cell Line ,GITR / NF-κB 荧光素酶报告基因 - Jurkat 细胞系,GITR / NF-κB Luciferase Reporter - Jurkat Cell Line
GITR / NF-κB 荧光素酶报告基因 - Jurkat 细胞系-GITR / NF-κB Luciferase Reporter - Jurkat Cell Line
产品货号:BPS-60546
产品规格:2 vials

糖皮质激素诱导的TNFR相关蛋白(GITR)是TNFR超家族成员之一,在t细胞、自然杀伤(NK)细胞和抗原呈递细胞(APC)等多种细胞中表达。GITRL是GITR的天然配体,主要由apc和GITR表达:GITRL相互作用对于激活免疫系统是重要的。靶向GITR的激动性抗体正被积极追求作为潜在的免疫肿瘤疗法。

该细胞系适合于监测响应于GITR配体(GITRL)的NF-kB信号传导的活性。

GITR / NF-κB 荧光素酶报告基因 - Jurkat 细胞系-GITR / NF-κB Luciferase Reporter - Jurkat Cell Line 收到后立即储存在液氮中。
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Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission
. In this study, we characterized the pharmacological profile of a novel curcumin analog P1 and elucidate the related mechanisms.Methods:HEK293/NF-κB cells, stably transfected with an NF-κB-responsive luciferase reporter plasmid, were generated for high-throughput
, as expected for direct regulation of the promoter. Those TFZF s that did not transactivate the promoter in the reporter assay (such as 144-4, 144-5, and 144-13) showed different activation profiles that varied depending on the cell line examined
. (2001)Genome Res. 11, 3–11 65. Sedimentation field flow fractionation purification of immature neural cells from a human tumor neuroblastoma cell line. Lautrette, C. et al. (2003)J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.791, 149–160 66. Flow
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