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细胞名称:CCMCL1 Mantle Cell Lymphoma Cell Line
货号:SCC132
种属:human
细胞系描述:Cancer Cells
应用:
CCMCL1 human mantle cell lymphoma cell line is well characterized at the molecular level and can support research and drug development efforts targeting MCL.
Research Category
Cancer
Oncology
This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation.
质量:
• Each vial contains ≥ 1X10^6 viable cells.
• Cells are tested negative for Epstein-Barr virus, HPV-16, HPV-18, Hepatitis A, C, Herpesvirus type 6, 7, 8 and HIV-1 & 2 viruses by PCR
• Cells are negative for mycoplasma contamination.
• Each lot of cells is genotyped by STR analysis to verify the unique identity of the cell line
储存及稳定性:CCMCL1 Mantle Cell Lymphoma Cell Line should be stored in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
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文献和实验Genomic Profiling of Mantle Cell Lymphoma
Genomic profiling of mantle cell lymphoma (MCL) cells has enabled a better understanding of the complex mechanisms underlying the pathogenesis of disease. Besides the t(11;14)(q13;q32) leading to cyclin D1 overexpression, MCL exhibits
Molecular Detection of t(11;14)(q13;q32) in Mantle Cell Lymphoma
Mantle cell lymphoma (MCL) is characterized by the presence of t(11;14)(q13;q32) which juxtaposes CCND-1 gene (also known as BCL-1 , PRAD-1 ) at 11q13 with an enhancer of the IGH@ gene at 14q32. The resultant overexpression of cyclin D1 plays
Evaluation of Homologous Recombinational Repair in Chicken B Lymphoma Cell Line, DT40
; however, in chicken B lymphoma cell line DT40, the ratio of targeted to random integration is extremely high. Although the underlying mechanism of this phenotype is not fully understood, DT40 has been utilized as a model cell line for a number of genetic analyses





