IL-6/IFN-β2/BSF-2,Human,Recombinant产品图

IL-6/IFN-β2/BSF-2,Human,Recomb

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  • ¥1480 - 19980
  • 普诺赛
  • PCK085
  • 国产
  • 2025年07月29日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存:

      现货

    • 供应商:

      上海经科化学科技有限公司

    • 规格:

      10μg/50μg/1mg/500μg

    规格:10μg产品价格:¥1480.0
    规格:50μg产品价格:¥3980.0
    规格:1mg产品价格:¥19980.0
    规格:500μg产品价格:¥13880.0

    产品信息

    别名 IFN-β2, B-Cell Differentiation Factor (BCDF), BSF-2, HPGF, HSF, MGI-2
    物种 Human
    表达宿主 E.coli
    序列信息 MVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM with polyhistidine tag at the C-terminus.
    检索号 P05231.1
    分子量 21.8 kDa
    表观分子量 22 kDa
    标签 His-tag at the C-terminus
    生物活性 Measure by its ability to induce proliferation in TF-1 cells. The ED50 for this effect is <0.5 ng/mL. The specific activity of recombinant human IL-6 is approximately >5 x 10^8 IU/mg.Measure by its ability to induce proliferation in MCF-7 cells. The ED50 for this effect is <4.4 ng/mL.

    产品特性

    纯度 >98% as determined by SDS-PAGE. Ni-NTA chromatography
    内毒素 <0.1 EU per 1 μg of the protein by the LAL method.
    保存 Lyophilized protein should be stored at -5~-20°C for 1 year. Upon reconstitution,store at 2-8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g.0.1% BSA,10%FBS,5%HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20°C or -80°C for 3-6 months.
    运输 Ambient temperature or ice pack.
    制剂 The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 8.0.
    复融 It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL.Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

    背景介绍

    Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. IL-6's role as an anti-inflammatory myokine is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1ra and IL-10.

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