CD158D

CD158D

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  • ¥1280 - 2180
  • Tanda
  • 中国
  • TD-31579
  • 2025年11月25日
  • FCM、ELISA
  • Mouse
  • Human
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  • 企业认证

    • 详细信息
    • 技术资料
    • 免疫原

      peptide

    • 亚型

      IgG1

    • 形态

      Liquid

    • 保存条件

      -20℃

    • 克隆性

      mAb

    • 适应物种

      Human

    • 保质期

      1年

    • 目录编号

      TD-31579

    • 级别

      科研级

    • 库存

      88

    • 供应商

      武汉天德

    • 宿主

      Mouse

    • 应用范围

      FCM、ELISA

    • 靶点

      详询

    • 抗体英文名

      Mouse Monoclonal Antibody to CD158D

    • 抗体名

      CD158D

    • 规格

      100ul/50ul

    规格:100ul产品价格:¥2180.0
    规格:50ul产品价格:¥1280.0

    Mouse Monoclonal Antibody to CD158D

     

    Description

    Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subs/ets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subs/ets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the "framework" loci that is present on all haplotypes. Alternate alleles of this gene are represented on multiple alternate reference loci (ALT_REF_LOCs). Alternative splicing results in multiple transcript variants, some of which may not be annotated on the primary reference assembly.

    Specification

    Aliases KIR2DL4; G9P; KIR103; KIR-2DL4; KIR103AS; KIR-103AS
    Entrez GeneID 3805
    Swissprot Q99706 
    clone 4C2D11
    WB Predicted band size 41.5kDa
    Host/Isotype Mouse IgG1
    Antibody Type Primary antibody
    Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
    Species Reactivity Human
    Immunogen Purified recombinant fragment of human CD158D (AA: extra 22-120) expressed in E. Coli.
    Formulation Purified antibody in PBS with 0.05% sodium azide

    Application

    FCM 1/200 - 1/400
    ELISA 1/10000

    Product Image

    • CD158D
      Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
    • CD158D
      Flow cytometric analysis of HL-60 cells using CD158D mouse mAb (green) and negative control (red).
     



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