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Anti-Mouse IL-12/IL-23 p40 PE

(100 μg)
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  • ¥3628
  • BioGems已认证
  • 83312-60-100
  • 2025年07月11日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 克隆性

      C17.8

    • 标记物

      PE

    • 规格

      100 μg

    Anti-Mouse IL-12/IL-23 p40 PE 同型对照:Rat IgG2a, kappa标记:PE

    IL-12 is a potent regulator of cell-mediated immune responses and it induces IFN-γ production
    by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and
    connective tissue-type mast cells. Among its biological activities, IL-12 promotes the growth
    and activity of activated NK, CD4+ and CD8+ cells, and induces the development of IFN-γ-
    producing Th1 cells.
    IL-23 is a proinflammatory, heterodimeric protein composed of two subunits: a unique p19
    subunit, and a p40 subunit that is shared with IL-12. IL-23 is secreted by activated dendritic
    cells and macrophages, and signals though a receptor comprised of IL-23R complexed with IL-
    12Rβ2. IL-23 has been shown to enhance proliferation of memory T cells. It also stimulates the
    production of IFN-γ in NK cells, induces IL-17 production, and drives Th17-mediated responses.

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    图标文献和实验
    相关实验
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    • 【转帖】Top 100 proteomics publications

      Top 100 proteomics publications ----From Ion Channel Media Group:ttp://www.ionchannelmedia.com/websites.php 1. Gavin et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature 2. Bonetta et al. (2006) Protein

    • Intracellular Immunofluorescent Staining for Flow Cytometry

      ConA (3ug/ml) (2d)/IL-2 (20ng/ml)+IL-4 (20ng/ml) (3d) 2d/3d anti-CD3 (10ug/ml immobilized) + anti-CD28 (2ug/ml soluble) 5hr Brefeldin A JES5-16E3 , JES5-2A5 IL-12/IL-23 (p40)

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