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- 英文名：
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现货库存
- 供应商：
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- 肿瘤类型：
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- 细胞类型：
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- 品系：
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- 组织来源：
ATCC/DSMZ/ECACC
- 相关疾病：
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- 物种来源：
人或动物
- 免疫类型：
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- 细胞形态：
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- 运输方式：
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| 种属 | 人 |
| 组织来源 | 正常冠状动脉组织 |
| 传代比例 | 1:2传代 |
| 完全培养基配置 | 基础培养基500ml ；生长添加剂5ml ；胎牛血清25ml ；双抗5ml |
| 简介 | 内皮细胞层是血液和其它组织的天然屏障。内皮细胞功能病变是造成动脉粥样硬化的主要原因。内皮细胞同时会合成 和分泌凝血和纤维蛋白溶解系统的增强和抑制物 ，以及影响血小板粘附和聚集的媒介物。它们同时也会分泌控制细胞 增殖的蛋白来维持血管壁的健康。人内皮细胞会分泌t-PA和PAI-1等抗血栓因子以及响应TNF-α , 继而分泌细胞因子 GM-CSF ，表达ICAM-1表面抗体 ，产生大量的一 氧 化 氮和endothelin。经皮冠状动脉腔内成形术（ PTCA ）造成的 内皮细胞受损和功能破坏可能是导致术后动脉再狭窄的重要原因。 |
| 形态 | 上皮细胞样 ，多角形细胞样 |
| 生长特征 | 贴壁生长 |
| 细胞检测 | 血管假性血友病因子（ vWF ）免疫荧光染色为阳性免疫荧光鉴定 ，细胞纯度可达90%以上 ，不含有HIV-1、HBV、 HCV、支原体、细菌、酵母和真菌等。 |
Interventional radiology plays a significant role in the treatment of bone metastases by various techniques, percutaneous or endovascular. Vertebroplasty is the most well-studied technique for stabilisation of spine metastases as it induces satisfactory stabilisation of the vertebra and offers clear improvement of the quality of life. Due to the success of this technique cementoplasty of other bones, mainly pelvic girdle, has been largely developed. The development of reinforced cementoplasty allows treatment of pre-fractural osteolysis of some long bones. The heat due to the polymerisation of the cement induces carcinolytic effect but this effect is not as important as that which results from radiofrequency destruction. This last technique appears currently as the most important development to definitively destroy bone metastases and is progressively replacing percutaneous alcoholic destruction of such lesions. Angiographic techniques, such as endovascular embolisation, can also be very useful to reduce the risk of surgical treatment of hyper vascular metastases. Chemoembolisation is currently developed to associate pain relief induced by Endovascular embolisation and the carcinolytic effect obtained by local endovascular chemotherapy. All these techniques should develop largely during the next years.
Exp Ther Med,2020,19(2) :1219-1224.towards novel immunotherapeutic strategies.The effects on immune cells and the inflammatory microenvironment of commonly applied cancer treatments (chemotherapeutic or biologic agents, interventional radiologic procedures) have become better appreciated. Likewise, the contribution of the immune system toward the effectiveness of these treatments is clearer. The relevance of
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文献和实验/LIP C, HAN J, ZHANG D, et al.
Effects ofdexmedeto- midineon oxidative stress and
inflammatory response in lungsduring
mechanicalventilation in COPD rats[J] .
Exp Ther Med,2020,19(2) :1219-1224.
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