LIPC,HAN J,ZHANG D,etal. Effectsofdexmedeto-midineonoxidativestressand inflammatoryresponseinlungsduring mechanicalventilationinCOPDrats[J]. Exp TherMed,2020,19(2) :1219-1224.towards novel immunotherapeutic strategies.The effects on immune cells and the inflammatory microenvironment of commonly applied cancer treatments (chemotherapeutic or biologic agents, interventional radiologic procedures) have become better appreciated. Likewise, the contribution of the immune system toward the effectiveness of these treatments is clearer. The relevance of