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- 文献和实验
- 技术资料
- 英文名:
/
- 库存:
现货库存
- 供应商:
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- 肿瘤类型:
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- 细胞类型:
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- 品系:
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- 组织来源:
ATCC/DSMZ/ECACC
- 相关疾病:
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- 物种来源:
人或动物
- 免疫类型:
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- 细胞形态:
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- 是否是肿瘤细胞:
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- 器官来源:
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- 运输方式:
常温或干冰
- 年限:
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- 生长状态:
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- 规格:
T25
| 种属 | 大鼠 |
| 组织来源 | 正常脂肪组织 |
| 传代比例 | 1:2传代 |
| 完全培养基配置 | 基础培养基500ml ;生长添加剂5ml ;胎牛血清50ml ;双抗5ml |
| 简介 | 脂肪组织在体内有在胞浆内积聚脂滴的成熟脂肪细胞和未在胞浆内积聚脂滴但有这种潜能的前脂肪细胞。前脂肪细胞 呈梭形 ,是一类具有增殖和向脂肪细胞分化能力的特异化了的前提细胞 ,与肥胖有着非常密切的关系。 |
| 形态 | 梭形细胞样 ,不规则细胞样 |
| 生长特征 | 贴壁生长 |
| 细胞检测 | 前脂肪细胞因子-1(Pref-1)免疫荧光染色为阳性免疫荧光鉴定 ,细胞纯度可达90%以上 ,不含有HIV-1、HBV、 HCV、支原体、细菌、酵母和真菌等。 |
human bone metastases when compared to a human normal epithelial cell line. All the analyzed genes were overexpressed in the tumor cells of breast cancer bone metastases when compared to normal breast tissue. We did not detect any differences between the expression of these genes in bone metastases from breast cancer or from other types of solid tumors. Importantly, there was a significant correlation between the expressions of IL11/CTGF, IL11/ADAMTS1, CTGF/CXCR4, CTGF/ADAMTS1, and MMP-1/ADAMTS1, supporting the cooperative function of these proteins in the bone microenvironment, and the potential functional role of these genes in the establishment of bone metastases in vivo.
Mycobacterium avium Complex[J]. (DDR1), a collagen receptor with tyrosine kinase activity5, instigates immune exclusion by promoting collagen fibre alignment. Ablation of Ddr1 in tumours promotes the intratumoral penetration of T cells and obliterates tumour growth in mouse models of TNBC. Supporting this
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文献和实验/
[20] CRILLY N P, AYEH S K, KARAKOUSIS P C.
The New Frontier of Host-Directed Therapies for
Mycobacterium avium Complex[J].
Front Immunol,
2020, 11: 623119.
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