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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Chimeric / Phosphatidylserine [Homo sapiens]
- 保存条件:
Store at -80℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 抗体英文名:
Bavituximab (Phosphatidylserine) Antibody, Monoclonal
- 抗体名:
Bavituximab (Phosphatidylserine) Antibody, Monoclonal
- 规格:
0.1mg
Bavituximab (Phosphatidylserine) 抗体, 单克隆,Bavituximab (Phosphatidylserine) Antibody, Monoclonal,Bavituximab (Phosphatidylserine) 抗体, 单克隆,Bavituximab (Phosphatidylserine) Antibody, Monoclonal
产品名称:Bavituximab (Phosphatidylserine) 抗体, 单克隆-Bavituximab (Phosphatidylserine) Antibody, Monoclonal
产品货号:PSI-10-170-0.1mg
产品规格:0.1mg
背景资料:Bavituximab is a chimeric Anti-PS monoclonal antibody analog which is used to potentially treat cancers and viral infections. It binds to phosphatidylserine and other exposed host cell lipids when induced by cellular stress. Additional analogs in the class include 3G4, 2aG4, 9d2 and Hu3g4.Bavituximab Anti-Cancer is a monoclonal antibody that binds to a basic component of the cell structure called a phospholipid that is exposed only on the surface of tumor blood vessel cells or on cells infected with certain viruses. Bavituximab binding to the tumor blood vessel cells alerts the body’s immune system to attack the tumor and its blood supply. This has been shown to inhibit tumor growth and development. Because in healthy cells the phospholipids are concealed inside the cell, the bavituximab does not bind to them. This targets the bavituximab to the malignant cells and potentially minimizes unwanted side effects.
保存建议:Bavituximab (Phosphatidylserine) 抗体, 单克隆-Bavituximab (Phosphatidylserine) Antibody, MonoclonalStore at -80℃
应用类型:
点击:Bavituximab (Phosphatidylserine) 抗体, 单克隆-Bavituximab (Phosphatidylserine) Antibody, Monoclonal查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验自己知识产权的人类新基因,前期的功能研究表明,它是促进细胞凋亡的增强剂.利用荧光 素(FITC)标记的TFAR19单克隆抗体为探针,对细胞凋亡过程中TFAR19蛋白的表达水平及定位研究发现,凋亡早期TFAR19表达水平增高并出 现快速核转位现象...查看原文 了解更多有用的、有意思的前沿资讯以及酷炫的实验方法,可以向大师兄申请微信好友 师兄微信号:shixiongcoming
单克隆抗体(50ng/ml;克隆CH-11,Oncor)诱导的Jurkat细胞的细胞凋亡。DeadEnd™比色法细胞凋亡检测系统标记Fas单克隆抗体处理过的细胞核(16小时),而未处理过的则未被染色(右下角插图)。Apoptosis is of Greek origin meaning "falling off". The term is used in an analogy to the apparent suicide of leaves resulting
正常细胞的磷酯酰丝氨(phosphatidylserine,PS)位于细胞膜内表面,细胞凋亡时翻转露于膜外侧,可与annexinV高亲合力结合。研究发现PS外翻为细胞凋亡的早期事件,先于膜通透性增加所51Cr或其他染料的释放。将效应细胞与靶细胞充分共育后,用PE结合的效应细胞特异性单克隆抗体(如CD8-PE)标记效应细胞(不能与PE-mABA结合的细胞即为靶细胞),再用FITC-annexin V标记凋亡靶细胞,用流式细胞仪区分并定量此三类不同的细胞群,即可计算出效应细胞杀伤靶细胞百分
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