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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD130
- 级别:
CD130 (gp130) Antibody
- 目录编号:
CD130 (gp130) Antibody
- 克隆性:
单克隆
- 抗原来源:
小鼠
- 保质期:
CD130 (gp130) Antibody
- 抗体英文名:
Dazzle™ 594 anti-human CD130 (gp130) Antibody-PE
- 抗体名:
CD130 (gp130) Antibody
- 标记物:
PE
- 宿主:
小鼠
- 适应物种:
人
- 免疫原:
CD130 (gp130) Antibody
- 亚型:
CD130 (gp130) Antibody
- 形态:
CD130 (gp130) Antibody
- 应用范围:
FC
- 保存条件:
2-8℃
- 浓度:
CD130 (gp130) Antibody
- 规格:
25 tests/100 tests
| 规格: | 25 tests | 产品价格: | ¥3000.0 |
|---|---|---|---|
| 规格: | 100 tests | 产品价格: | ¥6500.0 |
Description :CD130, also known as gp130 (glycoprotein 130), IL6ST (IL-6-receptor-associated signaltransducer), or common β chain, is a member of the hematopoietic cytokine receptor family.CD130 is a common subunit associated with the receptors for several cytokines, such as IL-6,IL-11, Oncostatin M (OSM), CNTF (ciliary neurotrophic factor), CT-1, Neuropoietin (NP), andIL-27. CD130 participates in the JAK-STAT signaling pathway and is expressed on T cells,activated B cells, monocytes, plasma cells, and endothelial or epithelial cells.
Verified Reactivity :Human
Antibody Type :Monoclonal
Host Species :Mouse
Immunogen :GP130 (23-619aa) recombinant protein
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation :The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 underoptimal conditions.
Concentration :Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent betitrated for optimal performance for each application.
* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.
Excitation Laser :Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)
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文献和实验非渗透性封闭缓冲液(用于细胞外抗原): PBS (D8537) 中含有5% 驴血清。 在4°C条件下,用150µl/孔相应稀释的一抗在相应的封闭缓冲液中孵育过夜。例如:抗I型胶原(Col-I)抗体(AB745)或抗纤维连接蛋白(FN)抗体(F0916)可在非渗透性封闭缓冲液中以1:50稀释使用。 用PBS(D8537)(200 µl/well)清洗三次,每次5-10分钟。 在室温下,用200µl/孔的适当荧光标记二抗在同一封闭缓冲液中相应稀释,孵育2小时。例如:Atto 488抗
广泛。 (一)CD的分类 迄今为止,CD的序号已从CD1命名至CD130(见附表)。可大致划分为T细胞、B细胞、激活细胞、髓样细胞、NK/非谱系细胞、血小板、内皮细胞、粘附分子和细胞因子受体等九个组(表6-1)。 (二)CD的应用 CD抗原及其相应的单克隆抗体在基础和临床免疫学研究中已得到广泛的应用,在基础免疫学研究中CD主要应用于:①CD抗原的基因克隆,新CD抗源及新配体的发现;②CD抗原结构与功能关系;③细胞激活途径和膜信号的传导;④细胞分化过程
of differentiation,CD)。在许多场合下,抗体及其识别的相应抗原都用同一个CD序号。 表6-1 抗人白细胞分化抗原McAb分组 分组 CD编号 T细胞










