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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD51/61
- 级别:
CD51/61 Antibody
- 目录编号:
CD51/61 Antibody
- 克隆性:
单克隆
- 抗原来源:
小鼠
- 保质期:
CD51/61 Antibody
- 抗体英文名:
anti-human CD51/61 Antibody-FITC
- 抗体名:
CD51/61 Antibody
- 标记物:
FITC
- 宿主:
小鼠
- 适应物种:
人
- 免疫原:
CD51/61 Antibody
- 亚型:
CD51/61 Antibody
- 形态:
CD51/61 Antibody
- 应用范围:
FC
- 保存条件:
2-8℃
- 浓度:
CD51/61 Antibody
- 规格:
25 tests/100 tests
| 规格: | 25 tests | 产品价格: | ¥1400.0 |
|---|---|---|---|
| 规格: | 100 tests | 产品价格: | ¥3200.0 |
anti-human CD51/61 Antibody-FITC详细如下:
Description :CD51/CD61 is an integrin complex known as α β . It is expressed at high levels on osteoclasts,endothelial cells, and melanoma cells and at low levels on platelets and macrophages. CD51 isa heterodimer composed of disulfide-linked 125 kD and 24 kD proteins. CD61 is also amember of the integrin family known as gpIIIa or β integrin. It is a 110 kD common β subunit ofCD51/CD61 or CD41/CD61 complex. CD51/CD61, also known as the vitronectin receptor,mediates the binding of platelets to immobilized vitronectin without prior activation. Otherligands include RGD-containing proteins such as fibrinogen, fibronectin, von Willebrand factor(vWf), laminin, thrombospondin and the neural adhesion molecule L1. CD51/CD61 alsomediates cell-cell adhesion via interaction with CD31. CD51/CD61 acts as an activationindependent receptor for platelet attachment and spreading on vitronectin and other RGDcontaining proteins, including matrix components. The 23C6 antibody has been reported to beuseful for blocking studies.
Verified Reactivity :Human
Reported Reactivity :African Green, Chicken, Cynomolgus, Rabbit
Antibody Type :Monoclonal
Host Species :Mouse
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation :The antibody was purified by affinity chromatography, and conjugated with FITC under optimalconditions.
Concentration :Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser :Blue Laser (488 nm)
Description :CD51/CD61 is an integrin complex known as α β . It is expressed at high levels on osteoclasts,endothelial cells, and melanoma cells and at low levels on platelets and macrophages. CD51 isa heterodimer composed of disulfide-linked 125 kD and 24 kD proteins. CD61 is also amember of the integrin family known as gpIIIa or β integrin. It is a 110 kD common β subunit ofCD51/CD61 or CD41/CD61 complex. CD51/CD61, also known as the vitronectin receptor,mediates the binding of platelets to immobilized vitronectin without prior activation. Otherligands include RGD-containing proteins such as fibrinogen, fibronectin, von Willebrand factor(vWf), laminin, thrombospondin and the neural adhesion molecule L1. CD51/CD61 alsomediates cell-cell adhesion via interaction with CD31. CD51/CD61 acts as an activationindependent receptor for platelet attachment and spreading on vitronectin and other RGDcontaining proteins, including matrix components. The 23C6 antibody has been reported to beuseful for blocking studies.
Verified Reactivity :Human
Reported Reactivity :African Green, Chicken, Cynomolgus, Rabbit
Antibody Type :Monoclonal
Host Species :Mouse
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation :The antibody was purified by affinity chromatography, and conjugated with FITC under optimalconditions.
Concentration :Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser :Blue Laser (488 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation):
1. Knapp WB, et al. 1989. Leucocyte Typing IV Oxford University Press. New York.
2. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
3. Horton M, et al. 1991. Exp. Cell Res. 195:368.
4. Takahashi R, et al. 1999. Blood 93:1951. (Block)
5. Davies J, et al. 1989. J. Cell Biol. 109:1817. (IF, IHC, IP)
6. Deregibus MC, et al. 2007. Blood doi:10.1182/blood-2007-03-078709. (FC, Block)
7. Barau A, et al. 2010. J. Ultrasound Med. 29:173. PubMed
Product Citations:
1. Wu W, et al. 2013. J Lipid Res. 54:936. PubMed
1. Knapp WB, et al. 1989. Leucocyte Typing IV Oxford University Press. New York.
2. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
3. Horton M, et al. 1991. Exp. Cell Res. 195:368.
4. Takahashi R, et al. 1999. Blood 93:1951. (Block)
5. Davies J, et al. 1989. J. Cell Biol. 109:1817. (IF, IHC, IP)
6. Deregibus MC, et al. 2007. Blood doi:10.1182/blood-2007-03-078709. (FC, Block)
7. Barau A, et al. 2010. J. Ultrasound Med. 29:173. PubMed
Product Citations:
1. Wu W, et al. 2013. J Lipid Res. 54:936. PubMed
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抗人 CD51/61 荧光标记FITC 抗体
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