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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD204
- 级别:
CD204 Antibody
- 目录编号:
CD204 Antibody
- 克隆性:
单克隆
- 抗原来源:
大鼠
- 保质期:
CD204 Antibody
- 抗体英文名:
Dazzle™ 594 anti-mouse CD204 Antibody-PE
- 抗体名:
CD204 Antibody
- 标记物:
PE
- 宿主:
大鼠
- 适应物种:
小鼠
- 免疫原:
CD204 Antibody
- 亚型:
CD204 Antibody
- 形态:
CD204 Antibody
- 应用范围:
FC
- 保存条件:
2-8℃
- 浓度:
0.2 mg/mL
- 规格:
25 ug/100 ug
| 规格: | 25 ug | 产品价格: | ¥3300.0 |
|---|---|---|---|
| 规格: | 100 ug | 产品价格: | ¥7400.0 |
Description :CD204, also known as scavenger receptor A (SR-A) and the macrophage scavenger receptor(MSR), is 220 kDa, trimeric type II transmembrane protein, with one scavenger receptorcysteine-rich domain (SRCR). It is a phagocytic pattern-recognition receptor (PRR) expressedon macrophages and dendritic cells. CD204 is a receptor mediating recognition andinternalization of low-density lipoprotein (LDL) by macrophages and plays a critical role inatherogenesis. CD204 also recognizes apoptotic cells, modified lipid proteins, and exogenouspathogen-associated molecular patterns (PAMPs), which results in the induction of innateimmune and inflammatory responses. CD204 can act as a co-receptor for Toll-like receptors,such as TLR3, TLR4, or TLR9, to facilitate the expression of proinflammatory cytokines.CD204 has been implicated in several pathological processes such as Alzheimer’s disease,sepsis, ischemic injury, and coronary artery disease.
Verified Reactivity :Mouse
Antibody Type :Monoclonal
Host Species :Rat
Immunogen :Recombinant mouse CD204 extracellular domain
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation :The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 underoptimal conditions.
Concentration :0.2 mg/mL
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per millioncells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance foreach application.
* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.
Excitation Laser :Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)
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