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文献和实验重大突破！甘波谊团队 Nature 首次报道第三种铁死亡抑制机制，提供抗癌新思路
by ferroptosis. Nature, (2019).2.C. Mao et al., DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer. Nature, (2021).3.S. Boukalova et al., Dihydroorotate dehydrogenase in oxidative phosphorylation and cancer. Biochim Biophys Acta Mol
Enzymatic Synthesis of (S)-Phenylalanine and Related (S)-Amino Acids by Phenylalanine Dehydrogenase
Phenylalanine dehydrogenase (L-phenylalanine: NAD+ oxidoreductase, deaminating [EC 1.4.1.20], PheDH) from Bacillus sphaericus R79a, overproduced in Escherichia coli JM109/pBPDH1-DBL, is active toward 3-substituted pyruvic acids with bulky
In 2002, mitochondrial aldehyde dehydrogenase (ALDH-2) was identified as an organic nitrate bioactivating enzyme. This so-called nitrate reductase activity denitrates nitroglycerin (glycerol trinitrate) to its 1,2-glycerol dinitrate
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