Description :CD94 is a 43/39 kD C-type lectin, also known as Kp43. It is present on all NK cells, NKT cells,and a subset of CD8-positive T lymphocytes in most mouse strains. CD94 is a type-IItransmembrane protein with an extracellular lectin-like domain and a short cytoplasmic tail.CD94 is expressed as a disulphide-linked heterodimer with a NKG2 subunit believed to mediatesignal transduction. When associated with NKG2A, the complex triggers inhibition; whenassociated with NKG2C, the complex triggers stimulation. The receptor complex of CD94 andNKG2 receptors bind to the ligand, Qa-1, and are thought to play a role in maintaining selftolerance in developing NK cells.
Verified Reactivity :Mouse
Antibody Type :Monoclonal
Host Species :Rat
Immunogen :CHO cells expressing the C57BL/6 alleles of CD94 and NKG2A
Preparation :The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 underoptimal conditions.
Concentration :0.2 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is =0.06 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Additional Product Notes :BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye moleculeremains the same, so you should expect the same quality and performance from our PE/Cyanine7products. Please contact Technical Service if you have any questions.