- ￥4100
- 齐源
- 362102
- 国产/进口
- 2025年07月09日
- FC, ICC, IP, Agonist
- 小鼠
- 人
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
CCX-CKR
- 级别：
CCX-CKR (CCRL1) Antibody
- 目录编号：
CCX-CKR (CCRL1) Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
CCX-CKR (CCRL1) Antibody
- 抗体英文名：
Purified anti-human CCX-CKR (CCRL1) Antibody
- 抗体名：
CCX-CKR (CCRL1) Antibody
- 标记物：
CCX-CKR (CCRL1) Antibody
- 宿主：
小鼠
- 适应物种：
人
- 免疫原：
CCX-CKR (CCRL1) Antibody
- 亚型：
CCX-CKR (CCRL1) Antibody
- 形态：
CCX-CKR (CCRL1) Antibody
- 应用范围：
FC, ICC, IP, Agonist
- 保存条件：
2-8℃
- 浓度：
0.5 mg/ml
- 规格：
100 µg
Purified anti-human CCX-CKR (CCRL1) Antibody详细如下：
Description ：Human CCX-CKR, also known as CCRL1, is a 40 kD, G-protein-coupled, seventransmembrane receptor. CCRL1 is a decoy receptor for CCL2, CCL8, CCL13, CCL19, CCL21and CCL25 that regulates chemotaxis of lymphocytes and cancer cells. Chemokine binding byCCX-CKR causes its internalization, reducing levels of available chemokine, and thusregulating migration of lymphocytes and cancerous cells. CCX-CKR is expressed by stromalcells of skin-draining lymph nodes, thymic epithelial cells, and immature dendritic cells (DCs). Alow CCX-CKR expression in tumor cells correlates with a poor survival rate of breast cancerpatients.
Verified Reactivity ：Human
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Full length CCX-CKR cDNA
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography.
Concentration ：0.5 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C.
Application ：FC - Quality tested、ICC, IP, Agonist - Reported in the literature, not verified in house
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
Description ：Human CCX-CKR, also known as CCRL1, is a 40 kD, G-protein-coupled, seventransmembrane receptor. CCRL1 is a decoy receptor for CCL2, CCL8, CCL13, CCL19, CCL21and CCL25 that regulates chemotaxis of lymphocytes and cancer cells. Chemokine binding byCCX-CKR causes its internalization, reducing levels of available chemokine, and thusregulating migration of lymphocytes and cancerous cells. CCX-CKR is expressed by stromalcells of skin-draining lymph nodes, thymic epithelial cells, and immature dendritic cells (DCs). Alow CCX-CKR expression in tumor cells correlates with a poor survival rate of breast cancerpatients.
Verified Reactivity ：Human
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Full length CCX-CKR cDNA
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography.
Concentration ：0.5 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C.
Application ：FC - Quality tested、ICC, IP, Agonist - Reported in the literature, not verified in house
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cellsin 100 µl volume. It is recommended that the reagent be titrated for optimal performance for eachapplication.
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation)：
1. Takatsuka, S. et al. 2011. J. Pharmacol. Toxicol. Methods. 63:250. (IF, IP, Agonist)
Product Citations：
1. Bryce S, et al. 2016. J Immunol. 196: 3341-3353. PubMed
2. Matti C, et al. 2020. Front Immunol. 11:720. PubMed
1. Takatsuka, S. et al. 2011. J. Pharmacol. Toxicol. Methods. 63:250. (IF, IP, Agonist)
Product Citations：
1. Bryce S, et al. 2016. J Immunol. 196: 3341-3353. PubMed
2. Matti C, et al. 2020. Front Immunol. 11:720. PubMed
文献支持
Purified 抗人 CCX-CKR (CCRL1) 抗体
￥4100
