TotalSeq™-A0215 抗人 CD268 (BAFF

TotalSeq™-A0215 anti-human CD268 (BAFF-R) Antibody详细如下：

Description ：B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. It belongs toTNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3(BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset.BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI andBCMA as well. The interaction of BAFF with BAFF-R promotes NF-κB activation and playspredominant roles in B-cell maturation and survival as well as costimulates T cell activation andproliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulatesBAFF-R-mediated NF-κB activation.

Verified Reactivity ：Human

Reported Reactivity ：African Green, Baboon, Cynomolgus, Rhesus

Antibody Type ：Monoclonal

Host Species ：Mouse

Immunogen ：BAFF-R-L1.2 transfectants

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 1 mM EDTA.

Preparation ：The antibody was purified by chromatography and conjugated with TotalSeq™-A oligomer underoptimal conditions.

Concentration ：0.5 mg/ml

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.

Application ：PG - Quality tested

Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis and the oligomer sequence is confirmed by sequencing. TotalSeq™-A antibodies arecompatible with 10x Genomics Single Cell Gene Expression Solutions.

To maximize performance, it is strongly recommended that the reagent be titrated for eachapplication, and that you centrifuge the antibody dilution before adding to the cells at 14,000xg at 2- 8°C for 10 minutes. Carefully pipette out the liquid avoiding the bottom of the tube and add to thecell suspension. For Proteogenomics analysis, the suggested starting amount of this reagent fortitration is ≤ 1.0 µg per million cells in 100 µL volume. Refer to the corresponding TotalSeq™protocol for specific staining instructions.