Sigma货号V900456-25g现货L-Glutathione reduced(γ-L-谷酰基-L-半胱氨酰-甘氨酸,GSH)上海睿安生物13611631389
L -还原型谷胱甘肽
≥98%,Vetec™
别名:γ-L-谷酰基-L-半胱氨酰-甘氨酸,GSH
说明
Amino Acid Sequence
γ-Glu-Cys-Gly
应用:可在5-10mM下用于从谷胱甘肽琼脂糖洗脱谷胱甘肽S-转移酶(GST)。
生化/生理作用
作为内源性抗氧化剂在减少细胞代谢和呼吸爆发期间生成的活性氧方面发挥重要作用。 谷胱苷肽S-转移酶催化异生素、白三烯和其他亲电子分子生成谷胱苷肽硫醚。 谷胱苷肽也和蛋白质半胱氨酸残基形成二硫键。 经由这些机制,它会产生降低抗癌药功效的逆反效应(paradoxical effect)。

同行评审论文(部分文献)
Minke whale genome and aquatic adaptation in cetaceans.
Hyung-Soon Yim et al.
Nature genetics, 46(1), 88-92 (2013-11-26)
The shift from terrestrial to aquatic life by whales was a substantial evolutionary event. Here we report the whole-genome sequencing and de novo assembly of the minke whale genome, as well as the whole-genome sequences of three minke whales, a
The AVR2-SIX5 gene pair is required to activate I-2-mediated immunity in tomato.
Lisong Ma et al.
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Plant-invading microbes betray their presence to a plant by exposure of antigenic molecules such as small, secreted proteins called 'effectors'. In Fusarium oxysporum f. sp. lycopersici (Fol) we identified a pair of effector gene candidates, AVR2-SIX5, whose expression is controlled
Ethylene Signaling Modulates Herbivore-Induced Defense Responses in the Model Legume Medicago truncatula.
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One or more effectors in the labial saliva (LS) of generalist Noctuid caterpillars activate plant signaling pathways to modulate jasmonate (JA)-dependent defense responses; however, the exact mechanisms involved have yet to be elucidated. A potential candidate in this phytohormone interplay
Adseverin plays a role in osteoclast differentiation and periodontal disease-mediated bone loss.
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(6), 2281-2291 (2015-02-15)
Osteoclast differentiation and function are highly dependent on the assembly and turnover of actin filaments, but little is known about the roles of actin binding proteins in these processes. Adseverin (Ads), a member of the gelsolin superfamily of actin capping
Cooperative binding of the outer arm-docking complex underlies the regular arrangement of outer arm dynein in the axoneme.
Mikito Owa et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(26), 9461-9466 (2014-07-01)
Outer arm dynein (OAD) in cilia and flagella is bound to the outer doublet microtubules every 24 nm. Periodic binding of OADs at specific sites is important for efficient cilia/flagella beating; however, the molecular mechanism that specifies OAD arrangement remains
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