- 询价
- BioLegend
- 119415
- BioLegend
- 2025年10月22日
4 年金牌会员
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 库存：
99
- 英文名：
PE/Cyanine7 anti-mouse CD134 (OX-40)
- 供应商：
北京云肽生物科技有限公司
BioLegend 119415 PE/Cyanine7 anti-mouse CD134 (OX-40)
北京云肽生物科技有限公司作为BioLegend的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。
美国BioLegend公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend虽然成立的时间不长，但它聚集了一批来自PharMingen公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。BioLegend公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。
BioLegend 119415 PE/Cyanine7 anti-mouse CD134 (OX-40)
产品简介：
产品品牌：BioLegend
产品货号：119415
产品名称：BioLegend 119415 PE/Cyanine7 anti-mouse CD134 (OX-40)
产品规格：25 µg
产品说明：
Clone OX-86 (See other available formats)
Regulatory Status RUO
Other Names TNFRSF4, ACT35, OX-40
Isotype Rat IgG1, κ
描述
CD134是一种I型整合膜蛋白，也称为OX-40、ACT35和肿瘤坏死因子受体超家族成员4（TNFRSF4）。该受体在活化的CD4+和CD8+T细胞以及B细胞上表达。OX-40受体与OX-40配体（CD252）结合以提供独立于CD28的共刺激信号。阻断OX40-OX40配体相互作用已被证明可以改善实验性EAE和炎症性肠病，这意味着这些相互作用在某些自身免疫性疾病的发病机制中很重要。
CD134 is a type I integral membrane protein also known as OX-40, ACT35, and tumor necrosis factor receptor superfamily member 4 (TNFRSF4). This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX-40 receptor binds to the OX-40 ligand (CD252) to provide a costimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, which implies that these interactions are important in the pathogenesis of some autoimmune diseases.
Product Details
Isotype Control PE/Cyanine7 Rat IgG1, κ Isotype Ctrl
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Immunogen Recombinant mouse OX-40-CD4 chimeric protein
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration 0.2 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes
Clone OX-86 has been reported to act as an agonist and stimulate OX-40.
Additional Product Notes
BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
Antigen Details
Structure TNF receptor superfamily, 50 kD
Distribution
Activated CD4+ and CD8+ T cells, activated B cells.
Function
Receptor for OX-40 ligand, provides co-stimulatory signal for lymphocyte proliferation independent of CD28; thought to play a role in the pathogenesis of some autoimmune diseases
Ligand/Receptor OX-40 ligand
Cell Type B cells, T cells, Tregs
Biology Area Immunology
Molecular Family CD Molecules, Immune Checkpoint Receptors
以下是BioLegend 品牌部分产品，如需其他产品请联系本公司销售。
BioLegend 104317 PE/Cyanine7 anti-mouse/rat CD61 2C9.G2 (HMβ3-1) 25 ug
BioLegend 104318 PE/Cyanine7 anti-mouse/rat CD61 2C9.G2 (HMβ3-1) 100 ug
BioLegend 104406 FITC anti-mouse CD62L MEL-14 500 ug
BioLegend 104407 PE anti-mouse CD62L MEL-14 50 ug
BioLegend 104408 PE anti-mouse CD62L MEL-14 200 ug
BioLegend 104410 PE/Cyanine5 anti-mouse CD62L MEL-14 100 ug
BioLegend 104411 APC anti-mouse CD62L MEL-14 25 ug
BioLegend 104412 APC anti-mouse CD62L MEL-14 100 ug
BioLegend 104419 Alexa Fluor® 488 anti-mouse CD62L MEL-14 25 ug
BioLegend 104420 Alexa Fluor® 488 anti-mouse CD62L MEL-14 100 ug
BioLegend 104421 Alexa Fluor® 647 anti-mouse CD62L MEL-14 25 ug
BioLegend 104423 Pacific Blue™ anti-mouse CD62L MEL-14 25 ug
BioLegend 104424 Pacific Blue™ anti-mouse CD62L MEL-14 100 ug
BioLegend 104426 Alexa Fluor® 700 anti-mouse CD62L MEL-14 100 ug
BioLegend 104429 PerCP anti-mouse CD62L MEL-14 25 ug
BioLegend 104430 PerCP anti-mouse CD62L MEL-14 100 ug
BioLegend 104431 PerCP/Cyanine5.5 anti-mouse CD62L MEL-14 25 ug
BioLegend 104437 Brilliant Violet 605™ anti-mouse CD62L MEL-14 125 uL
BioLegend 104438 Brilliant Violet 605™ anti-mouse CD62L MEL-14 50 ug
BioLegend 104440 Brilliant Violet 785™ anti-mouse CD62L MEL-14 50 ug
BioLegend 104445 Brilliant Violet 711™ anti-mouse CD62L MEL-14 50 ug
BioLegend 104447 PE/Dazzle™ 594 anti-mouse CD62L MEL-14 25 ug
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验相关实验
7211011 小鼠淋巴细胞分离液 达优 100339 Ultra-LEAF™ Purified anti-mouse CD3ε Antibody BioLegend 102115 Ultra-LEAF™ Purified anti-mouse CD28 Antibody BioLegend CD3/CD28 Streptamer® 多聚体法： 货号 名称
CD3/ CD4 /CD8 T cell subset counts
Description Procedure for CD3/ CD4 /CD8 T cell subset counts using CD3-FITC / CD4-PE / CD8-PECy5 antibody Procedure 1. One 5 ml round bottom tube (Falcon) is taken per blood sample to be analyzed. The tube is labeled, which includes
CD3/ CD4 /CD8 T cell subset counts
Description Procedure for CD3/ CD4 /CD8 T cell subset counts using CD3-FITC / CD4-PE / CD8-PECy5 antibody Procedure 1. One 5 ml round bottom tube (Falcon) is taken per blood sample to be analyzed. The tube is labeled, which includes
技术资料暂无技术资料 索取技术资料
BioLegend 119415 PE/Cyanine7 anti-mouse CD134 (OX-40)
询价
