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99
- 英文名：
BioLegend 109819 Pacific Blue™ anti-mouse CD45.2
- 供应商：
北京云肽生物科技有限公司
BioLegend 109819 Pacific Blue™ anti-mouse CD45.2
北京云肽生物科技有限公司作为BioLegend的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。
美国BioLegend公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend虽然成立的时间不长，但它聚集了一批来自PharMingen公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。BioLegend公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。
BioLegend 109819 Pacific Blue™ anti-mouse CD45.2
产品简介：
产品品牌：BioLegend
产品货号：109819
产品名称：BioLegend 109819 Pacific Blue™ anti-mouse CD45.2
产品规格：25 µg
产品说明：
Clone 104 (See other available formats)
Regulatory Status RUO
Other Names Ly-5.2, LCA
Isotype Mouse (SJL) IgG2a, κ
描述
CD45.2是CD45的同种异体抗原，由携带Ly5.2的小鼠株（例如，A、AKR、BALB/c、CBA/Ca、CBA/J、C3H/He、C57BL、C57BR、C57L、C58、DBA/1、DBA/2、NZB、SWR、129）表达。CD45是蛋白酪氨酸磷酸酶（PTP）家族的成员，是一种180-240kD的糖蛋白，在除成熟红细胞和血小板外的所有造血细胞上表达。小鼠体内存在多种亚型，在TCR和BCR信号转导中发挥关键作用。这些亚型对细胞的激活和成熟状态以及特定的细胞类型都是非常特异的。CD45的主要配体是半乳糖凝集素-1、CD2、CD3、CD4、TCR、CD22和Thy-1。
CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
Product Details
Isotype Control Pacific Blue™ Mouse IgG2a, κ Isotype Ctrl
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Mouse
Immunogen B10.S mouse thymocytes and splenocytes
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions.
Concentration 0.5 mg/ml
Storage & Handling The CD45.2 antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is highly recommended that the reagent be titrated for optimal performance for each application.
* Pacific Blue™ has a maximum emission of 455 nm when it is excited at 405 nm. Prior to using Pacific Blue™ conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
View full statement regarding label licenses
Excitation Laser Violet Laser (405 nm)
Application Notes
The 104 antibody does not react with mouse cells expressing the CD45.1 alloantigen. Additional reported applications (for the relevant formats) include: immunoprecipitation4, in vivo and in vitro blocking of B cell responses1,2, and immunohistochemical staining of *-fixed frozen sections3.
Antigen Details
Structure Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution
All hematopoietic cells except mature erythrocytes and platelets of the CD45.2 strain of mice
Function Phosphatase, T and B cell activation
Ligand/Receptor Galectin-1, CD2, CD3, CD4
Biology Area Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family CD Molecules
以下是BioLegend 品牌部分产品，如需其他产品请联系本公司销售。
BioLegend 101617 PerCP/Cyanine5.5 anti-mouse CD23 B3B4 25 ug
BioLegend 101621 Brilliant Violet 421™ anti-mouse CD23 B3B4 50 ug
BioLegend 101623 Brilliant Violet 510™ anti-mouse CD23 B3B4 50 ug
BioLegend 101629 APC/Cyanine7 anti-mouse CD23 B3B4 25 ug
BioLegend 101630 APC/Cyanine7 anti-mouse CD23 B3B4 100 ug
BioLegend 101632 Alexa Fluor® 700 anti-mouse CD23 B3B4 100 ug
BioLegend 101637 Brilliant Violet 605™ anti-mouse CD23 B3B4 50 ug
BioLegend 101642 APC/Fire™ 750 anti-mouse CD23 B3B4 100 ug
BioLegend 101801 Purified anti-mouse CD24 M1/69 50 ug
BioLegend 101804 Biotin anti-mouse CD24 M1/69 500 ug
BioLegend 101805 FITC anti-mouse CD24 M1/69 50 ug
BioLegend 101806 FITC anti-mouse CD24 M1/69 500 ug
BioLegend 101807 PE anti-mouse CD24 M1/69 50 ug
BioLegend 101808 PE anti-mouse CD24 M1/69 200 ug
BioLegend 101814 APC anti-mouse CD24 M1/69 100 ug
BioLegend 101818 Alexa Fluor® 647 anti-mouse CD24 M1/69 100 ug
BioLegend 101819 Pacific Blue™ anti-mouse CD24 M1/69 25 ug
BioLegend 101820 Pacific Blue™ anti-mouse CD24 M1/69 100 ug
BioLegend 101821 PE/Cyanine7 anti-mouse CD24 M1/69 25 ug
BioLegend 101822 PE/Cyanine7 anti-mouse CD24 M1/69 100 ug
BioLegend 101823 PerCP/Cyanine5.5 anti-mouse CD24 M1/69 25 ug
BioLegend 101824 PerCP/Cyanine5.5 anti-mouse CD24 M1/69 100 ug
北京云肽生物科技有限公司作为BioLegend的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。
美国BioLegend公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend虽然成立的时间不长，但它聚集了一批来自PharMingen公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。BioLegend公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。
BioLegend 109819 Pacific Blue™ anti-mouse CD45.2
产品简介：
产品品牌：BioLegend
产品货号：109819
产品名称：BioLegend 109819 Pacific Blue™ anti-mouse CD45.2
产品规格：25 µg
产品说明：
Clone 104 (See other available formats)
Regulatory Status RUO
Other Names Ly-5.2, LCA
Isotype Mouse (SJL) IgG2a, κ
描述
CD45.2是CD45的同种异体抗原，由携带Ly5.2的小鼠株（例如，A、AKR、BALB/c、CBA/Ca、CBA/J、C3H/He、C57BL、C57BR、C57L、C58、DBA/1、DBA/2、NZB、SWR、129）表达。CD45是蛋白酪氨酸磷酸酶（PTP）家族的成员，是一种180-240kD的糖蛋白，在除成熟红细胞和血小板外的所有造血细胞上表达。小鼠体内存在多种亚型，在TCR和BCR信号转导中发挥关键作用。这些亚型对细胞的激活和成熟状态以及特定的细胞类型都是非常特异的。CD45的主要配体是半乳糖凝集素-1、CD2、CD3、CD4、TCR、CD22和Thy-1。
CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
Product Details
Isotype Control Pacific Blue™ Mouse IgG2a, κ Isotype Ctrl
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Mouse
Immunogen B10.S mouse thymocytes and splenocytes
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions.
Concentration 0.5 mg/ml
Storage & Handling The CD45.2 antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is highly recommended that the reagent be titrated for optimal performance for each application.
* Pacific Blue™ has a maximum emission of 455 nm when it is excited at 405 nm. Prior to using Pacific Blue™ conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
View full statement regarding label licenses
Excitation Laser Violet Laser (405 nm)
Application Notes
The 104 antibody does not react with mouse cells expressing the CD45.1 alloantigen. Additional reported applications (for the relevant formats) include: immunoprecipitation4, in vivo and in vitro blocking of B cell responses1,2, and immunohistochemical staining of *-fixed frozen sections3.
Antigen Details
Structure Protein tyrosine phosphatase (PTP) family, 180-240 kD
Distribution
All hematopoietic cells except mature erythrocytes and platelets of the CD45.2 strain of mice
Function Phosphatase, T and B cell activation
Ligand/Receptor Galectin-1, CD2, CD3, CD4
Biology Area Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family CD Molecules
以下是BioLegend 品牌部分产品，如需其他产品请联系本公司销售。
BioLegend 101617 PerCP/Cyanine5.5 anti-mouse CD23 B3B4 25 ug
BioLegend 101621 Brilliant Violet 421™ anti-mouse CD23 B3B4 50 ug
BioLegend 101623 Brilliant Violet 510™ anti-mouse CD23 B3B4 50 ug
BioLegend 101629 APC/Cyanine7 anti-mouse CD23 B3B4 25 ug
BioLegend 101630 APC/Cyanine7 anti-mouse CD23 B3B4 100 ug
BioLegend 101632 Alexa Fluor® 700 anti-mouse CD23 B3B4 100 ug
BioLegend 101637 Brilliant Violet 605™ anti-mouse CD23 B3B4 50 ug
BioLegend 101642 APC/Fire™ 750 anti-mouse CD23 B3B4 100 ug
BioLegend 101801 Purified anti-mouse CD24 M1/69 50 ug
BioLegend 101804 Biotin anti-mouse CD24 M1/69 500 ug
BioLegend 101805 FITC anti-mouse CD24 M1/69 50 ug
BioLegend 101806 FITC anti-mouse CD24 M1/69 500 ug
BioLegend 101807 PE anti-mouse CD24 M1/69 50 ug
BioLegend 101808 PE anti-mouse CD24 M1/69 200 ug
BioLegend 101814 APC anti-mouse CD24 M1/69 100 ug
BioLegend 101818 Alexa Fluor® 647 anti-mouse CD24 M1/69 100 ug
BioLegend 101819 Pacific Blue™ anti-mouse CD24 M1/69 25 ug
BioLegend 101820 Pacific Blue™ anti-mouse CD24 M1/69 100 ug
BioLegend 101821 PE/Cyanine7 anti-mouse CD24 M1/69 25 ug
BioLegend 101822 PE/Cyanine7 anti-mouse CD24 M1/69 100 ug
BioLegend 101823 PerCP/Cyanine5.5 anti-mouse CD24 M1/69 25 ug
BioLegend 101824 PerCP/Cyanine5.5 anti-mouse CD24 M1/69 100 ug
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BioLegend 109819 Pacific Blue™ anti-mouse CD45.2
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