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- 库存：
99
- 英文名：
Pacific Blue™ anti-human CD7
- 供应商：
北京云肽生物科技有限公司
BioLegend 343132 Pacific Blue™ anti-human CD7
北京云肽生物科技有限公司作为 BioLegend 的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。
美国 BioLegend 公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend 虽然成立的时间不长，但它聚集了一批来自 PharMingen 公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。
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BioLegend 343132 Pacific Blue™ anti-human CD7
产品简介：
产品品牌：BioLegend
产品货号：343132
产品名称：BioLegend 343132 Pacific Blue™ anti-human CD7
产品规格：100 tests
产品说明：
Clone CD7-6B7 (See other available formats)
Regulatory Status RUO
Workshop IV T-164
Other Names gp40
Isotype Mouse IgG2a, κ
描述
CD7 是一种 40 kD 的 I 型跨膜糖蛋白，也称为 gp40。它是在T细胞，NK细胞，胸腺细胞，造血祖细胞和单核细胞（弱）上发现的免疫球蛋白超家族的成员。CD7也在急性淋巴细胞白血病（ALL）和一些急性髓系白血病（AML）细胞上表达。CD7交联诱导T淋巴细胞中的钙通量，可能是细胞质结构域与PI3激酶相关的结果。CD7共刺激可诱导细胞因子分泌并调节细胞粘附。
CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.
Product Details
Isotype Control Pacific Blue™ Mouse IgG2a, κ Isotype Ctrl
Verified Reactivity Human
Antibody Type Monoclonal
Host Species Mouse
Immunogen KG1a cell line
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with Pacific Blue™ under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
View full statement regarding label licenses
Excitation Laser Violet Laser (405 nm)
Application Notes
Additional reported (for the relevant formats) applications include proteogenomics2.
Antigen Details
Structure
Ig superfamily, type I transmembrane glycoprotein, 40 kD
Distribution
T cells, NK cells, thymocytes, hematopoietic progenitors, myeloid leukemic cell subsets
Function T cell activation
Ligand/Receptor
Cytoplasmic domain associates with P13-kinase
Cell Type
Hematopoietic stem and progenitors, Leukemia, NK cells, T cells, Thymocytes
Biology Area Costimulatory Molecules, Immunology
Molecular Family CD Molecules
以下是 BioLegend 品牌部分产品，如需其他产品请联系本公司销售。
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文献和实验相关实验
度的功能细胞。二、人外周血中 CD4 T 细胞分选实例1.产品信息： MojoSort™ Human CD4 T Cell Isolation Kit（BioLegend, Cat#480009），阴性分选试剂盒2.检测仪器型号：BD LSRⅡ3.样本：正常人外周血4.分选前后检测相关产品：PE-CD4（Biolegend, Cat# 317410）5.实验过程（1）采血之后采用达优™ 人淋巴细胞分离液分离人外周血单个核细胞。分离之后能见到明显的白膜层。（达优，Cat#DKW-KLSH-0100
Cell Surface Immunofluorescence Staining Protocol
实验试剂 Cell Staining Buffer [ Details:BioLegend Cat. #420201] Red Cell Lysis Buffer [ Details: BioLegend Cat. #420301] 7-AAD Viability Staining Solution[ Details: BioLegend Cat. #420403] TruStain FcX™[ Details: anti
Live‐Cell Immunofluorescence Staining of Human Pluripotent Stem Cells
cells in human pluripotent stem cell cultures, whereas hCD29 recognizes an antigen expressed on undifferentiated and many differentiated cells. A distinguishing feature of hCD29 in live?cell staining is that its antigen is precluded from detection
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BioLegend 343132 Pacific Blue™ anti-human CD7
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