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- 2025年10月20日
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- 库存：
99
- 英文名：
Purified anti-mouse CD279 (PD-1)
- 供应商：
北京云肽生物科技有限公司
北京云肽生物科技有限公司作为BioLegend的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。
美国BioLegend公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend虽然成立的时间不长，但它聚集了一批来自PharMingen公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。BioLegend公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。
BioLegend 109101 Purified anti-mouse CD279 (PD-1)
产品简介：
产品品牌：BioLegend
产品货号：109101
产品名称：BioLegend 109101 Purified anti-mouse CD279 (PD-1)
产品规格：50 µg
产品说明：
Clone RMP1-30 (See other available formats)
Regulatory Status RUO
Other Names Programmed Death-1, CD279
Isotype Rat IgG2b, κ
描述
CD279是一个50-55kD的免疫球蛋白超家族成员，也称为程序性死亡-1（PD-1）。PD-1在CD4-CD8-胸腺细胞亚群以及活化的T和B细胞上表达。PD-1被认为参与淋巴细胞克隆选择和外周耐受。PD-1配体PD-L1（也称为B7-H1）和PD-L2（B7-DC）是B7免疫球蛋白超家族的成员。
CD279 is a 50-55 kD immunoglobulin superfamily member also known as programmed death-1 (PD-1). PD-1 is expressed on a subset of CD4-CD8- thymocytes and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily.
Product Details
Isotype Control Purified Rat IgG2b, κ Isotype Ctrl
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Immunogen Mouse PD-1 transfected BHK cells
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography.
Concentration 0.5 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C.
Application FC - Quality tested
IHC-F - Verified
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes
The RMP1-30 antibody does not block the binding of PD-1 to B7-H1 and B7-DC1.
Antigen Details
Structure Ig superfamily, 50-55 kD
Distribution Subset of double negative thymocytes, activated T and B cells
Function Lymphocyte clonal selection, peripheral tolerance
Ligand/Receptor PD-L1 (B7-H1), PD-L2
Cell Type B cells, T cells, Thymocytes, Tregs
Biology Area Apoptosis/Tumor Suppressors/Cell Death, Cancer Biomarkers, Cell Biology, Immunology, Inhibitory Molecules
Molecular Family CD Molecules, Immune Checkpoint Receptors
以下是BioLegend 品牌部分产品，如需其他产品请联系本公司销售。
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BioLegend 101325 APC anti-mouse CD16/32 93 25 ug
BioLegend 101328 APC/Cyanine7 anti-mouse CD16/32 93 100 ug
BioLegend 101332 Brilliant Violet 421™ anti-mouse CD16/32 93 50 ug
BioLegend 101333 Brilliant Violet 510™ anti-mouse CD16/32 93 50 ug
BioLegend 101335 Purified anti-mouse CD16/32 (Maxpar® Ready) 93 100 ug
BioLegend 101339 Ultra-LEAF™ Purified anti-mouse CD16/32 93 5 mg
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BioLegend 101407 PE anti-mouse CD18 M18/2 50 ug
BioLegend 101505 FITC anti-mouse CD19 MB19-1 50 ug
BioLegend 101506 FITC anti-mouse CD19 MB19-1 500 ug
BioLegend 101602 Purified anti-mouse CD23 B3B4 500 ug
BioLegend 101605 FITC anti-mouse CD23 B3B4 50 ug
BioLegend 101607 PE anti-mouse CD23 B3B4 50 ug
BioLegend 101608 PE anti-mouse CD23 B3B4 200 ug
BioLegend 101609 Alexa Fluor® 488 anti-mouse CD23 B3B4 100 ug
BioLegend 101613 PE/Cyanine7 anti-mouse CD23 B3B4 25 ug
BioLegend 101614 PE/Cyanine7 anti-mouse CD23 B3B4 100 ug
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