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- BioLegend
- 162703
- BioLegend
- 2025年10月26日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
99
- 英文名：
PE anti-mouse AhR
- 供应商：
北京云肽生物科技有限公司
北京云肽生物科技有限公司作为 BioLegend 的特约经销商，为广大客户提供原装正品，货期短，折扣好的服务准则。
美国 BioLegend 公司位于美国加州，致力于为生物医药研究的各个前沿领域提供高质量的抗体及其它相关试剂。BioLegend 虽然成立的时间不长，但它聚集了一批来自 PharMingen 公司的专业人士，建立了一支具有雄厚技术背景的专业队伍。通过其自身的先天优势，以及与世界知名实验室和研究所的良好合作关系，以合理的价格为广大客户提供高质量的免疫学和细胞生物学产品。
BioLegend 公司以其专业技术力量为保证，提供各种质量卓越的产品，并不断地开发新产品，以满足飞速发展的生命科学研究的需要。
BioLegend 162703 PE anti-mouse AhR
产品简介：
产品品牌：BioLegend
产品货号：162703
产品名称：BioLegend 162703 PE anti-mouse AhR
产品规格：25 µg
产品说明：
Clone W16012C (See other available formats)
Regulatory Status RUO
Other Names
bHLHe76, aryl hydrocarbon receptor, Aryl hydrocarbon receptor, RP85
Isotype Rat IgG2b, κ
描述
芳烃受体或AhR是一种bHLH转录因子，由TCDD等配体激活。它在许多免疫细胞中表达，并在免疫调节中发挥重要作用。AhR在TH17极化条件下被诱导。在非活性状态下，AhR存在于细胞质中，并且在配体结合后它易位到细胞核。AhR 的活化受到泛素化、配体代谢和复杂破坏的严格控制。
Aryl Hydrocarbon Receptor or AhR is a bHLH transcription factor that is activated by ligands such as TCDD. It is expressed in many immune cells and perform an important role in immune regulation. AhR is induced under TH17-polarizing conditions. In its inactive state, AhR presents in the cytoplasm, and upon ligand binding it translocates to the nucleus. Activation of AhR is tightly controlled by Ubiquitination, ligand metabolism, and complex disruption.
Product Details
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Rat
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration 0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application ICFC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
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