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- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
2209911-80-6
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥3333.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥1430.0 |
| 规格: | 5 mg | 产品价格: | ¥3230.0 |
| 规格: | 10 mg | 产品价格: | ¥5170.0 |
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P-CAB agent 2 hydrochloride
CAS No. : 2209911-80-6
MCE 国际站:P-CAB agent 2 hydrochloride
产品活性:P-CAB agent 2 hydrochloride 是一种有效的且具有口服活性的钾竞争性酸 (potassium-competitive acid) 阻滞剂和胃酸分泌抑制剂。P-CAB agent 2 hydrochloride 抑制 H+/K+-ATPase 活性,IC50 值为 <100 nM。P-CAB agent 2 hydrochloride 抑制 hERG 钾通道,IC50 值为 18.69 M。P-CAB agent 2 hydrochloride 无急性毒性并抑制组胺 (HY-B1204) -诱导的胃酸分泌。
研究领域:Membrane Transporter/Ion Channel
作用靶点:Potassium Channel
In Vitro: P-CAB agent 2 hydrochloride (100 µM) inhibits the hERG potassium channel with an inhibition rate of 86.21% and an IC50 value of 18.69 M.
In Vivo: P-CAB agent 2 hydrochloride (example 1) inhibits histamine (HY-B1204)-induced gastric acid secretion in SD rats.
P-CAB agent 2 hydrochloride (600, 2000 mg/kg; p.o.; once) shows no acute toxicity and 600mg/kg shows no significant effect on animal body weight in SD rats.
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文献和实验RNase P Ribozyme As an Antiviral Agent Against Human Cytomegalovirus
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Catalytic M1GS RNA as an Antiviral Agent in Animals
The use of RNase P ribozyme (M1GS catalytic RNA) for inhibition of murine cytomegalovirus (MCMV) propagation in mice is described in this chapter. General information about RNase P based technology is included and followed by detailed
Targeting mRNAs by Engineered Sequence-Specific RNase P Ribozymes
The methods of using engineered RNase P catalytic RNA (termed as M1GS RNA) for in vitro and in vivo in trans-cleavage of target viral mRNA are described in this chapter. Detailed information is focused on (1) mapping accessible regions
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