ENT-C225,2919962-53-9

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

ENT-C225

CAS No. : 2919962-53-9

MCE 国际站：ENT-C225

产品活性：ENT-C225 是一种有效的 TrkB 神经营养素受体激活剂。ENT-C225 对激活 TrkB 受体 (TrkBR) 的效力较高，并且具有较好的物理化学特性和神经保护特性。

研究领域：Neuronal Signaling  |  Protein Tyrosine Kinase/RTK

作用靶点：Trk Receptor

In Vitro: ENT-C225 (Compound 10) (1 µM; 24 h) significantly improves NIH-3T3 TrkB cytotoxicity and reduces cell mortality.
ENT-C225 (1 µM; 20 min) promotes TrkB receptor phosphorylation in NIH-3T3 TrkB cells and primary astrocytes.
ENT-C225 (500 pM-1 µM; 48 h) has significant neuroprotective effect and enhances in a dose-dependent manner. ENT-C225 promoting the accumulation of TAR DNA-binding protein 43 (TDP43) in the neural network and cytoplasm of spinal motor neurons.

相关产品：Entrectinib  |  Larotrectinib  |  ANA-12  |  7,8-Dihydroxyflavone  |  Repotrectinib  |  Sitravatinib  |  K-252a  |  Amitriptyline hydrochloride  |  GW 441756  |  GNF-5837  |  Lestaurtinib  |  Selitrectinib  |  N-Acetyl-5-hydroxytryptamine  |  LM22B-10  |  Altiratinib  |  AZ-23  |  Tyrphostin AG 879  |  Tamnorzatinib  |  Cyclotraxin B  |  LM22A-4  |  Tavilermide  |  Belizatinib  |  DS-1205b free base  |  TrkA-IN-1  |  PF-6683324  |  CH7057288  |  2-Bromo-6-methoxynaphthalene  |  GNF-8625 monopyridin-N-piperazine hydrochloride

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Dye Reagents  |  PROTAC  |  Isotope-Labeled Compounds