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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
96
- 靶点:
详询
- 级别:
科研
- 目录编号:
/
- 克隆性:
多克隆
- 抗原来源:
/
- 保质期:
1年
- 抗体英文名:
Anti-IFNK
- 抗体名:
IFNK抗体
- 标记物:
详询
- 宿主:
兔
- 适应物种:
/
- 免疫原:
KLH conjugated synthetic peptide derived from human IFNK
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 应用范围:
WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
详询
| 英文名称 Anti-IFNK |
| 中文名称 干扰素kappa蛋白抗体 |
| 别 名 IFN kappa; IFN-kappa; Ifnk; IFNK_HUMAN; Interferon kappa. |
| 浓 度 1mg/1ml |
| 规 格 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human |
| 产品类型 一抗 |
研究领域 细胞生物 细胞因子 ![]() |
| 蛋白分子量 predicted molecular weight: 22kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human IFNK |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 |
| (石蜡切片需做抗原修复) |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. ![]() |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 IFNK is a member of the type I interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. This protein is expressed in keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster. |
| Function : May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pathway. It is able to directly modulate cytokine release from monocytes and dendritic cells. Binds heparin. |
| Subcellular Location : Secreted. |
| Tissue Specificity : Expressed in keratinocytes, monocytes and in resting dendritic cells. |
| Similarity : Belongs to the alpha/beta interferon family. |
Database links : UniProtKB/Swiss-Prot: Q9P0W0.2![]() |
| fgL2 (Fibrinogen-like 2) 凝血酶原酶 (又称:纤维介素蛋白;前凝血素) |
| FLIP S/L (Flice-like Inhibitory Protein) 凋亡调节基因之一(抗原) |
| FoxP3 叉头蛋白3-T细胞转录因子(多肽抗原) |
| GAD-65 (glutamate decarboxylase) 谷氨酸脱羧酶-65(抗原) |
| GAP-43 ( Growth associated protein-43 ) 生长相关蛋白-43(抗原) |
| Gastrin 胃泌素(抗原) |
| GFAP(Glial Fibrillary Acidic Protein) 胶质纤维酸性蛋白(抗原) |
| MMP-1(matrix metalloproteinases-1) 基质金属蛋白酶-1(抗原) |
| MMP-2(Collagenase IV /Gelatinase A/Metallo proteinase-2) 基质金属蛋白酶-2(多肽抗原) |
| MMP-3(matrix metalloproteinase-3/Transin-1/SL-1/Stromelysin-1 precursor) 基质金属蛋白酶-3(抗原) |
| MMP-7(Matrilysin/matrix metalloproteinases-7) 基质金属蛋白酶-7(抗原) |
| MMP-14(Matrix metalloproteinase-14) 金属基质蛋白酶-14 |
| GFRα-1(GDNF family receptor alpha-1) GDNF家族受体α-1(抗原) |
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文献和实验免疫组织化学技术(immunohistochemistry)
和抗体标记技术的改进,特别是自70年代中期杂交瘤技术与单克隆抗体技术的引入,使制备的抗体具有高度的特异性。简便而敏感的免疫酶标技术能够用于普通培养细胞(株)、常规福尔马林固定石蜡包埋的组织切片、若干年前的存档标本等,从而使该技术在生物医学研究和临床病理学、微生物学诊断中,日益显示出巨大的实用价值。目前主要应用在如下几个方面: 1确定细胞类型 通过特定抗体标记出细胞内相应抗原成分,以确定细胞类型。如角蛋白是上皮性标记,前列腺特异性抗原仅见于前列腺上皮,甲状腺球蛋白抗体
免疫组织化学技术(immunohistochemistry)简介
成分,以确定细胞类型。如角蛋白是上皮性标记,前列腺特异性抗原仅见于前列腺上皮,甲状腺球蛋白抗体是甲状腺滤泡型癌的敏感标记,而降钙素抗体是甲状腺髓样癌的特有标记。有些细胞(如表皮内朗格汉斯细胞、黑色素细胞、淋巴结内指突状和树突状网织细胞)光镜下不易辨认,但免疫组化标记(S-100蛋白等)能清楚显示其形态。 2 辨认细胞产物 利用某些细胞产物为抗原制备的抗体,可作为相应产物的特殊标记,如内分泌细胞产生的各种激素,大多数可用免疫组化技术标记出来,据此可对内分泌肿瘤作
连接靶细胞和效应细胞的作用,同时还刺激NK细胞合成和分泌肿瘤坏死因子和γ干扰素等细胞因子,并释放颗粒,溶解靶细胞。嗜酸性粒细胞发挥ADCC作用是通过其FcεRⅡ和FcαR介导的,嗜酸性粒细胞可脱颗粒释放碱性蛋白等,在杀伤寄生虫如蠕虫中发挥重要作用。 抗体依赖的细胞介导的细胞毒作用(ADCC) 此外,人IgGFc段能非特异地与葡萄菌A蛋白(staphylococcus proteinA,SPA)结合,应用SPA可纯化IgG













