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- 详细信息
- 文献和实验
- 技术资料
- 抗体英文名:
Angiopoietin-2 Antibody
- 抗原:
synthetic peptide corresponding to residues surrounding Lys275 of mouse angiopoietin-2
- 应用范围:
W
- 宿主:
Rabbit
- 库存:
大量
- 供应商:
CST
- 保质期:
详见说明书
- 适应物种:
M
- 级别:
详见MSDS文件
- 是否单克隆:
2
- 保存条件:
-20°c
- 规格:
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格: | 产品价格: | ¥请询价 | |
|---|---|---|---|
| 规格: | 100 ul (10 western blots) | 产品价格: | ¥请询价 |
| 规格: | carrier free & custom formulation / quantity | 产品价格: | ¥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting
Reactivity Key: M=Mouse
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W | M | Transfected Only | 66 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | Angiopoietin-2 Antibody detects transfected levels of mouse angiopoietin-2 protein. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Lys275 of mouse angiopoietin-2. Antibodies are purified by peptide affinity chromatography. |
| Background | Angiopoietins are a family of Tie receptor ligands. There are four angiopoietins discovered so far: angiopoietins 1, 2, 3 and 4 (Ang1, 2, 3, and 4) (1-3). Ang1 binds to the Tie-2 receptor and leads to its autophosphorylation and subsequent activation of downstream signaling pathways. It plays an important role in blood vessel formation, maturation and subsequent stabilization (1,4,5). Ang2 is an endothelium-specific growth factor that functions as an antagonist to Ang1, promotes vascular associated proinflammatory function, destabilizes quiescent endothelium, leads to vascular leakage and vascular destablization and remodeling (2,6,7). Ang2 is selectively expressed in many tumor tissues where, combined with other growth factors such as VEGF, it can promote vascular remodeling, angiogenesis and inflammation (7-9).
|
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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文献和实验人血管生成素-1(Angiopoietin-1)ELISA试剂盒 说明书
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人血管生成素-1 (Angiopoietin-1)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 Angiopoietin-1 单抗包被于酶标板上,标准品和样品中的
人血管生成素-2(Angiopoietin-2)ELISA试剂盒 说明书
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人血管生成素-2 (Angiopoietin-2)ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和唾液等其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 Angiopoietin-2 单抗包被于酶标板上,标准品和样品中的
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
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