- 询价
- Cell Signaling Technology
- 3136
- USA
- 2026年05月28日
- W
- H,M,R
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- 文献和实验
- 技术资料
- 抗体英文名：
CDK6 (DCS83) Mouse mAb
- 抗原：
recombinant human CDK6 corresponding to amino acids 30-65
- 应用范围：
W
- 级别：
详见MSDS文件
- 适应物种：
H,M,R
- 供应商：
CST
- 保质期：
详见说明书
- 库存：
大量
- 是否单克隆：
1
- 保存条件：
-20°c
- 规格：
40 ul (8 western blots)/100 ul (20 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 40 ul (8 western blots) | 产品价格： | ￥请询价 |
| 规格： | 100 ul (20 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting
Reactivity Key: H=Human M=Mouse R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Isotype |
|---|---|---|---|---|
| W | H M R | Endogenous | 36 | Mouse IgG1 |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | CDK6 (DCS83) Mouse mAb detects endogenous levels of total CDK6 protein. |
| Source / Purification | Monoclonal antibody is produced by immunizing animals with recombinant human CDK6 corresponding to amino acids 30-65. Western Blotting
Western blot analysis of extracts from HeLa, IM-CD-3 and C6 cells, using CDK6 (DCS83) Mouse mAb. |
| Background | The cyclin-dependent kinases form complexes with their cyclin partners and with CDK inhibitors. CDK6 and CDK4 associate with the D-type cyclins and target the retinoblastoma protein, allowing passage through the G1/S phase restriction point (1). CDK6/cyclin D complexes are sequestered in their inactive form through binding to one of the INK4 CDK inhibitor family members (2,3). Unlike the INK4 family of cdk inhibitors, the CDK inhibitor p21 Waf1/Cip1 may enhance the association of CDK4 and CDK6 with their cyclin D partners (4). |
| Application References |
Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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文献和实验DCs in Mouse Models of Intracellular Bacterial Infection
Direct infection of antigen-presenting cells (APCs) with living intracellular bacteria may influence the early innate immune response as well as the following T-cell response. Revealing the identity of primarily targeted cells
Generation of Large Numbers of Pro-DCs and Pre-DCs In Vitro
. In this chapter, we describe the very simple method of generating large numbers of in vitro-derived pro-DCs and pre-DCs. As these precursors are largely DC-restricted, they can be used to either reconstitute a mouse with DCs of desired background, to study
(adjust pH to 7.8 with Binding buffer; red color) to the Protein A column.Mouse antibodies of the IgG1 subclass do not have a high affinity for protein A. Purification on protein A beads using standard conditions will yield approximately 1/10
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