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抗人elmo2多克隆抗体
- 参考价格： ¥1100.0 - 2310.0
- 品 牌： abgent
- 货 号： AP11106c
- 适应物种： 人
- 应用范围： 免疫印迹,免疫组化,流式细胞技术
- 克 隆 性： 多克隆
- 亚 型： Rabbit Ig
- 抗体类型： 一抗
产品概览
| 背景： | The protein encoded by this gene interacts with thededicator of cyto-kinesis 1 protein. Similarity to a C. elegansprotein suggests that this protein may function in phagocytosis ofapoptotic cells and in cell migration. Alternative splicing resultsin multiple transcript variants encoding the same protein.REFERENCESBento, J.L., et al. Genomics 92(4):226-234(2008)Rikova, K., et al. Cell 131(6):1190-1203(2007)Zhang, Y., et al. Mol. Cell Proteomics 4(9):1240-1250(2005)Zhang, Y., et al. Mol. Cell Proteomics 4(9):1240-1250(2005)Castelo, R., et al. Nucleic Acids Res. 33(6):1935-1939(2005) |
| 其他名字： | ELMO2; CED12A; KIAA1834; Engulfment and cell motility protein 2; Protein ced-12 homolog A |
产品特性
| 预测型适应物种： | Mouse, Bovine |
靶点信息
| 基因id： | 63916 |
| 蛋白名： | ELMO2 |
| 胞内定位： | Cytoplasm. Cytoplasm, cytosol. Membrane. |
| 同义词： | CED12A, KIAA1834 |
应用与保存
| 稀释浓度： | WB~~1:1000WB~~1:1000IHC~~1:50~100FC~~1:10~50 |
| 注意事项： | ELMO2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
其他
| 参考文献： | Bento, J.L., et al. Genomics 92(4):226-234(2008)Rikova, K., et al. Cell 131(6):1190-1203(2007)Zhang, Y., et al. Mol. Cell Proteomics 4(9):1240-1250(2005)Zhang, Y., et al. Mol. Cell Proteomics 4(9):1240-1250(2005)Castelo, R., et al. Nucleic Acids Res. 33(6):1935-1939(2005) |
| 保存条件： | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| 标记物： | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| 主要序列号： | Q96JJ3 |
| 其他序列号： | Q8BHL5,A4FUD6,NP_877496.1,NP_573403.1 |
| 分子量： | 82615 Da |
| 功能： | Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. |
| 规格： | 80 µl (8 western blots) | 价格： | ¥1100.00 |
| 规格： | 400 µl (40 western blots) | 价格： | ¥2310.00 |
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